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Yuen-Sum Lau

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Articles 22
Citations 525
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Recent Articles
1.
Ohia-Nwoko O, Montazari S, Lau Y, Eriksen J
Mol Neurodegener . 2014 Nov; 9:54. PMID: 25432085
Background: Recent epidemiological evidence suggests that modifying lifestyle by increasing physical activity could be a non-pharmacological approach to improving symptoms and slowing disease progression in Alzheimer's disease and other tauopathies....
2.
Wang X, Escano C, Asico L, Jones J, Barte A, Lau Y, et al.
Hypertension . 2013 Jun; 62(2):295-301. PMID: 23753418
D3 dopamine receptor (D3R)-deficient mice have renin-dependent hypertension associated with sodium retention, but the hypertension is mild. To determine whether any compensatory mechanisms in the kidney are involved in the...
3.
Lau Y, Blouin R, Brixner D, Crismon L, Cutler S, Ho R, et al.
Am J Pharm Educ . 2012 Nov; 76(8):S14. PMID: 23129861
No abstract available.
4.
Patki G, Lau Y
Neurosci Lett . 2011 Nov; 505(3):268-72. PMID: 22040668
The etiology of neurodegenerative disorders like Parkinson's disease remains unknown, although many genetic and environmental factors are suggested as likely causes. Neuronal oxidative stress and mitochondrial dysfunction have been implicated...
5.
Patki G, Lau Y
Pharmacol Biochem Behav . 2011 Jul; 99(4):704-11. PMID: 21741988
Neuronal oxidative stress and mitochondrial dysfunction have been implicated in Parkinson's disease. Melatonin is a natural antioxidant and free radical scavenger that has been shown to effectively reduce cellular oxidative...
6.
Lau Y, Patki G, Das-Panja K, Le W, Ahmad S
Eur J Neurosci . 2011 Mar; 33(7):1264-74. PMID: 21375602
The protective impact of exercise on neurodegenerative processes has not been confirmed, and the mechanisms underlying the benefit of exercise have not been determined in human Parkinson's disease or in...
7.
Weinman E, Biswas R, Steplock D, Wang P, Lau Y, Desir G, et al.
Am J Physiol Renal Physiol . 2011 Feb; 300(5):F1123-9. PMID: 21325500
The current experiments explore the role of dopamine in facilitating the acute increase in renal phosphate excretion in response to a high-phosphate diet. Compared with a low-phosphate (0.1%) diet for...
8.
Patki G, Che Y, Lau Y
Front Aging Neurosci . 2010 Jun; 1:3. PMID: 20552054
Mitochondrial oxidative stress and dysfunction has been implicated as a possible mechanism for the onset and progression of Parkinson-like neurodegeneration. However, long-term mitochondrial defects in chronic animal neurodegenerative models have...
9.
Escano C, Armando I, Wang X, Asico L, Pascua A, Yang Y, et al.
Am J Physiol Regul Integr Comp Physiol . 2009 Sep; 297(6):R1660-9. PMID: 19726707
The C57Bl/6J mouse strain, the genetic background of many transgenic and gene knockout models, is salt sensitive and resistant to renal injury. We tested the hypothesis that renal dopaminergic function...
10.
Barber-Singh J, Seo B, Nakamaru-Ogiso E, Lau Y, Matsuno-Yagi A, Yagi T
Rejuvenation Res . 2009 Aug; 12(4):259-67. PMID: 19653878
Previously, we showed that the internal rotenone-insensitive nicotinamide adenine dinucleotide (NADH)-quinone oxidoreductase (NDI1) gene from Saccharomyces cerevisiae (baker's yeast) can be successfully inserted into the mitochondria of mice and rats...