Yuelong Yan
Overview
Explore the profile of Yuelong Yan including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
1473
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0
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Recent Articles
1.
Yan Y, Zhuang L, Gan B
Cell Metab
. 2024 Nov;
36(11):2355-2356.
PMID: 39504935
Transmembrane receptor proteins are proficient in sensing external signals and initiating downstream pathways to control cell survival. Lin et al. demonstrated that GPR56, a G-protein-coupled receptor, can be activated by...
2.
Mao C, Lei G, Horbath A, Wang M, Lu Z, Yan Y, et al.
Mol Cell
. 2024 May;
84(10):1964-1979.e6.
PMID: 38759628
The role of the mitochondrial electron transport chain (ETC) in regulating ferroptosis is not fully elucidated. Here, we reveal that pharmacological inhibition of the ETC complex I reduces ubiquinol levels...
3.
Jiang D, Guo Y, Wang T, Wang L, Yan Y, Xia L, et al.
Nat Commun
. 2024 May;
15(1):4114.
PMID: 38750057
Cellular sensitivity to ferroptosis is primarily regulated by mechanisms mediating lipid hydroperoxide detoxification. We show that inositol-requiring enzyme 1 (IRE1α), an endoplasmic reticulum (ER) resident protein critical for the unfolded...
4.
5.
Lei G, Mao C, Horbath A, Yan Y, Cai S, Yao J, et al.
Cancer Discov
. 2024 Mar;
14(8):1476-1495.
PMID: 38552003
Resistance to poly (ADP-ribose) polymerase inhibitors (PARPi) limits the therapeutic efficacy of PARP inhibition in treating breast cancer susceptibility gene 1 (BRCA1)-deficient cancers. Here we reveal that BRCA1 has a...
6.
Liu X, Chen Z, Yan Y, Zandkarimi F, Nie L, Li Q, et al.
Protein Cell
. 2024 Mar;
15(9):686-703.
PMID: 38430542
Ferroptosis has been recognized as a unique cell death modality driven by excessive lipid peroxidation and unbalanced cellular metabolism. In this study, we established a protein interaction landscape for ferroptosis...
7.
Yan Y, Gan B
Life Metab
. 2024 Jan;
2(6).
PMID: 38179338
The lack of a reliable and specific marker for ferroptosis has hindered the advancement of treatments related to this cell death mechanism toward clinical application. A recent study published in...
8.
Yan Y, Zhang C, Hao J, Wang X, Ming J, Mi L, et al.
PLoS Biol
. 2023 Nov;
21(11):e3002379.
PMID: 37944100
[This corrects the article DOI: 10.1371/journal.pbio.3000324.].
9.
Mao C, Liu X, Yan Y, Olszewski K, Gan B
Nature
. 2023 Jul;
619(7968):E19-E23.
PMID: 37407682
No abstract available.
10.
Yan Y, Teng H, Hang Q, Kondiparthi L, Lei G, Horbath A, et al.
Nat Commun
. 2023 Jun;
14(1):3673.
PMID: 37339981
The cystine transporter solute carrier family 7 member 11 (SLC7A11; also called xCT) protects cancer cells from oxidative stress and is overexpressed in many cancers. Here we report a surprising...