Yue-Ru Chu
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Explore the profile of Yue-Ru Chu including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
243
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0
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Recent Articles
1.
Chung K, Hsu S, Chu Y, Lin M, Jiaang W, Chen R, et al.
PLoS One
. 2014 Feb;
9(2):e88772.
PMID: 24551161
Background: The ability of human bone marrow mesenchymal stem cells (BM-MSCs) to migrate and localize specifically to injured tissues is central in developing therapeutic strategies for tissue repair and regeneration....
2.
Huang C, Chu Y, Ye Y, Chen X
J Biol Chem
. 2013 Dec;
289(7):4444-54.
PMID: 24366871
Misfolded proteins of the endoplasmic reticulum (ER) are retrotranslocated to the cytosol and degraded by the proteasome via a process termed ER-associated degradation (ERAD). The precise mechanism of retrotranslocation is...
3.
Huang C, Hsiao H, Chu Y, Ye Y, Chen X
J Biol Chem
. 2013 Jul;
288(35):25330-25339.
PMID: 23867461
Endoplasmic reticulum-associated degradation (ERAD) is an important system that eliminates misfolded proteins from the ER. Three derlins have been implicated in this process, but their precise function remains unknown. In...
4.
Chen X, Tukachinsky H, Huang C, Jao C, Chu Y, Tang H, et al.
J Cell Biol
. 2011 Mar;
192(5):825-38.
PMID: 21357747
The Hedgehog (Hh) signaling pathway has important functions during metazoan development. The Hh ligand is generated from a precursor by self-cleavage, which requires a free cysteine in the C-terminal part...
5.
Wu J, Tang H, Yeh T, Chen C, Shy H, Chu Y, et al.
Biochem Pharmacol
. 2009 May;
78(2):203-10.
PMID: 19439267
DPP-IV (EC 3.4.14.5) is a validated drug target for human type II diabetes. DPP-IV inhibitors without DPP8/9 inhibitory activity have been sought because a possible association has been reported between...
6.
Tang H, Tang H, Hsu S, Chu Y, Chien C, Shu C, et al.
Arch Biochem Biophys
. 2009 Mar;
485(2):120-7.
PMID: 19268648
Dipetidyl peptidase 9 (DPP9) is a prolyl dipeptidase preferentially cleaving the peptide bond after the penultimate proline residue. The biological function of DPP9 is unknown. In this study, we have...
7.
Lin H, Yang M, Wu C, Chen P, Yang Y, Chu Y, et al.
Int J Cancer
. 2007 Aug;
121(11):2547-55.
PMID: 17680560
The major obstacle for the treatment of gastric cancer is recurrence and metastasis; yet, its molecular mechanism is largely unknown. 2-methoxyestradiol (2-ME), a metabolite of the estradiol-17beta, has recently been...
8.
Perng C, Kao C, Yang Y, Lin H, Lin W, Chu Y, et al.
J Biomed Mater Res A
. 2007 Jul;
84(3):622-30.
PMID: 17635011
Skin tissue engineering is a possible solution for the treatment of extensive skin defect. The ultimate goal of skin tissue engineering is to restore the complete functions of native skin,...