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Yuanzhu Xiong

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Citations 576
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Recent Articles
1.
Gu H, Zhou Y, Yang J, Li J, Peng Y, Zhang X, et al.
FASEB J . 2021 Jan; 35(2):e21308. PMID: 33481304
Peroxisome proliferator-activated receptor gamma (PPARγ) is a master regulator of adipogenesis and lipogenesis. To understand its roles in fiber formation and fat deposition in skeletal muscle, we successfully generated muscle-specific...
2.
Zhang L, Zhou Y, Wu W, Hou L, Chen H, Zuo B, et al.
Int J Biol Sci . 2017 Nov; 13(9):1152-1162. PMID: 29104506
Individual skeletal muscles in the animal body are heterogeneous, as each is comprised of different fiber types. Type I muscle fibers are rich with mitochondria, and have high oxidative metabolisms...
3.
Ying F, Gu H, Xiong Y, Zuo B
Biomed Res Int . 2017 Apr; 2017:5404682. PMID: 28386555
Adipose tissue was the major energy deposition site of the mammals and provided the energy for the body and released the external pressure to the internal organs. In animal production,...
4.
Ying F, Zhang L, Bu G, Xiong Y, Zuo B
Biochem Biophys Res Commun . 2016 Dec; 480(4):669-674. PMID: 27983980
The peroxisome proliferator-activated receptor gamma, co-activator 1 alpha(PGC1α) effectively induced the biosynthesis of the mitochondria and the energy metabolism, and also regulated the muscle fiber-type shift. Overexpression of PGC1α gene...
5.
Liu X, Wang Y, Hou L, Xiong Y, Zhao S
J Cell Physiol . 2016 Dec; 232(7):1893-1906. PMID: 27966786
Fibroblast growth factor 21(FGF21) is a pivotal regulator of energy metabolism, which is currently being assessed as a potential drug target for the treatment of insulin-resistant conditions. However, the cellular...
6.
Kang T, Peng D, Bu G, Gu H, Zhang F, Zhang R, et al.
Gene . 2016 Oct; 595(1):92-98. PMID: 27688071
FAM3A (family with sequence similarity 3, member A) is regulated by PPARG and participates in the metabolism of lipid in liver. However, the transcriptional regulation analysis of FAM3A is very...
7.
Li Y, Li J, Fang C, Shi L, Tan J, Xiong Y, et al.
Sci Rep . 2016 May; 6:26852. PMID: 27229484
Some documented evidences proved small RNAs (sRNA) and targeted genes are involved in mammalian testicular development and spermatogenesis. However, the detailed molecular regulation mechanisms of them remain largely unknown so...
8.
Zhang R, Feng X, Zhan M, Huang C, Chen K, Tang X, et al.
Int J Mol Sci . 2016 Jan; 17(1). PMID: 26784181
Rho-associated, coiled-coil containing protein kinase 1 (ROCK1) gene plays a crucial role in maintaining genomic stability, tumorigenesis and myogenesis. However, little is known about the regulatory elements governing the transcription...
9.
Wang Y, Liu X, Hou L, Wu W, Zhao S, Xiong Y
Int J Mol Sci . 2015 Dec; 17(1). PMID: 26703591
Fibroblast growth factor 21 (FGF21) plays an important role in the treatment of disease associated with muscle insulin resistance which is characterized by various factors, such as intramuscular triglyceride (IMT)...
10.
Wu X, Ji P, Zhang L, Bu G, Gu H, Wang X, et al.
PLoS One . 2015 Dec; 10(12):e0144851. PMID: 26659441
Peroxiredoxin6 (Prdx6) is one of the peroxiredoxin (Prdxs) family members that play an important role in maintaining cell homeostasis. Our previous studies demonstrated that Prdx6 was significantly associated with pig...