Yuanxin Xu
Overview
Explore the profile of Yuanxin Xu including associated specialties, affiliations and a list of published articles.
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Articles
52
Citations
1059
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Recent Articles
1.
Zeng Y, Xiao J, Shi L, Li Y, Xu Y, Zhou J, et al.
Eur J Med Chem
. 2025 Feb;
:117400.
PMID: 40011151
No abstract available.
2.
Zeng Y, Xiao J, Shi L, Li Y, Xu Y, Zhou J, et al.
Eur J Med Chem
. 2025 Feb;
287:117293.
PMID: 39923533
Targeted protein degradation through autophagosome-tethering compounds (ATTECs) that bypasses the ubiquitination process has garnered increasing attention. LC3B, a key protein in autophagosome formation, recruits substrates into the autophagy-lysosome system for...
3.
Tounekti O, Prior S, Wassmer S, Xu J, Wong A, Fang X, et al.
Bioanalysis
. 2025 Jan;
17(3):105-149.
PMID: 39862111
The 18 Workshop on Recent Issues in Bioanalysis (18 WRIB) took place in San Antonio, TX, USA on May 6-10, 2024. Over 1100 professionals representing pharma/biotech companies, CROs, and multiple...
4.
5.
Fontana M, Solomon S, Kachadourian J, Walsh L, Rocha R, Lebwohl D, et al.
N Engl J Med
. 2024 Nov;
391(23):2231-2241.
PMID: 39555828
Background: Transthyretin amyloidosis with cardiomyopathy (ATTR-CM) is a progressive, often fatal disease. Nexiguran ziclumeran (nex-z) is an investigational therapy based on CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats and associated...
6.
Cohn D, Gurugama P, Magerl M, Katelaris C, Launay D, Bouillet L, et al.
N Engl J Med
. 2024 Oct;
392(5):458-467.
PMID: 39445704
Background: Hereditary angioedema is a rare genetic disease characterized by severe and unpredictable swelling attacks. NTLA-2002 is an in vivo gene-editing therapy that is based on clustered regularly interspaced short...
7.
Xu Y, Jiang Y, Xu L, Zhou W, Zhang Z, Qi Y, et al.
Lipids Health Dis
. 2024 Aug;
23(1):259.
PMID: 39169399
Background: Left ventricular hypertrophy (LVH) is a critical factor in heart failure and cardiovascular event-related mortality. While the prevalence of LVH in diabetic patients is well-documented, its occurrence and risk...
8.
Mora J, Palmer R, Wagner L, Wu B, Partridge M, Meena , et al.
Bioanalysis
. 2024 Feb;
16(7):77-119.
PMID: 38389403
The 17 Workshop on Recent Issues in Bioanalysis (17 WRIB) took place in Orlando, FL, USA on June 19-23, 2023. Over 1000 professionals representing pharma/biotech companies, CROs, and multiple regulatory...
9.
Longhurst H, Lindsay K, Petersen R, Fijen L, Gurugama P, Maag D, et al.
N Engl J Med
. 2024 Jan;
390(5):432-441.
PMID: 38294975
Background: Hereditary angioedema is a rare genetic disease that leads to severe and unpredictable swelling attacks. NTLA-2002 is an in vivo gene-editing therapy based on clustered regularly interspaced short palindromic...
10.
Zeng Y, Xiao J, Xu Y, Wei F, Tian L, Gao Y, et al.
J Med Chem
. 2023 Sep;
66(18):12877-12893.
PMID: 37671907
Autophagy is an efficient and attractive protein degradation pathway in addition to the ubiquitin-proteasome system. Herein, systematic optimization of coumarin analogs linked with the CDK9 inhibitor SNS-032 is reported that...