Yuanjian Huang
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Explore the profile of Yuanjian Huang including associated specialties, affiliations and a list of published articles.
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39
Citations
323
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Recent Articles
1.
Zhang Z, Cheng X, Huang Y, Wang D, Lv X, Chang X
J Agric Food Chem
. 2025 Feb;
73(7):3887-3896.
PMID: 39913168
The utilization of novel organic synthesis methods is increasingly critical in the development of innovative agrochemicals. In this study, we designed and synthesized a series of chiral oxazoline derivatives using...
2.
Cheng X, Zhang Z, Huang Y, Wang F, Wang D, Lv X, et al.
Pest Manag Sci
. 2025 Jan;
PMID: 39816005
Background: Development of novel chiral antifungal agents for effective control of plant pathogens is urgently needed. In this study, a series of pyrazol-5-yl-benzamide derivatives containing chiral oxazoline moiety were rationally...
3.
Seo Y, Jang J, Ko K, Zou G, Huang Y, Zhang S, et al.
bioRxiv
. 2025 Jan;
PMID: 39763993
Diffuse gastric adenocarcinoma (DGAC) is an aggressive malignancy with limited therapeutic options, poor prognosis, and poorly understood biology. CRACD, an actin polymerization regulator, is often inactivated in gastric cancer, including...
4.
Kim B, Huang Y, Ko K, Zhang S, Zou G, Zhang J, et al.
Nat Commun
. 2024 Oct;
15(1):9169.
PMID: 39448571
Cell plasticity, changes in cell fate, is crucial for tissue regeneration. In the lung, failure of regeneration leads to diseases, including fibrosis. However, the mechanisms governing alveolar cell plasticity during...
5.
Feng X, Yang C, Huang Y, Su D, Wang C, Wilson L, et al.
Proc Natl Acad Sci U S A
. 2024 Sep;
121(39):e2406325121.
PMID: 39298484
Immune evasion is not only critical for tumor initiation and progression, but also determines the efficacy of immunotherapies. Through iterative in vivo CRISPR screens with seven syngeneic tumor models, we...
6.
Kim B, Zhang S, Huang Y, Ko K, Jung Y, Jang J, et al.
Cell Rep
. 2024 May;
43(6):114286.
PMID: 38796854
Tumor cell plasticity contributes to intratumoral heterogeneity and therapy resistance. Through cell plasticity, some lung adenocarcinoma (LUAD) cells transform into neuroendocrine (NE) tumor cells. However, the mechanisms of NE cell...
7.
Ko K, Zhang S, Huang Y, Kim B, Zou G, Jun S, et al.
iScience
. 2024 May;
27(5):109795.
PMID: 38741711
Despite the promising outcomes of immune checkpoint inhibitors (ICIs), resistance to ICI presents a new challenge. Therefore, selecting patients for specific ICI applications is crucial for maximizing therapeutic efficacy. Herein,...
8.
Jie Y, Qin H, Jia B, Tian M, Lou S, Liu G, et al.
Sci Total Environ
. 2024 Apr;
933:172784.
PMID: 38679101
Climate change and human activities have great impacts on runoff. With the gradual development of cascade hydropower in the watershed, the reservoirs have increasingly impacted runoff. However, the current study...
9.
Yang S, Zhang D, Sun Q, Nie H, Zhang Y, Wang X, et al.
Cancer Res
. 2024 Apr;
84(13):2202-2217.
PMID: 38657117
Colorectal cancer is one of the most common malignant tumors in humans, with liver metastasis being the primary cause of mortality. The epithelial-mesenchymal transition (EMT) process endows cancer cells with...
10.
Zou G, Huang Y, Zhang S, Ko K, Kim B, Zhang J, et al.
J Exp Med
. 2024 Feb;
221(4).
PMID: 38411616
Diffuse-type gastric adenocarcinoma (DGAC) is a deadly cancer often diagnosed late and resistant to treatment. While hereditary DGAC is linked to CDH1 mutations, the role of CDH1/E-cadherin inactivation in sporadic...