Yuan-Liang Zhang
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Explore the profile of Yuan-Liang Zhang including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
166
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0
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Recent Articles
1.
Li N, Wang Z, Zhang F, Feng C, Chen Y, Liu D, et al.
FEBS J
. 2024 Apr;
291(15):3367-3383.
PMID: 38652546
l-threonine dehydrogenase (Tdh) is an enzyme that links threonine metabolism to epigenetic modifications and mitochondria biogenesis. In vitro studies show that it is critical for the regulation of trimethylation of...
2.
Zhang Y, Wang X, Xu C, Liu N, Zhang L, Zhang Y, et al.
Front Cell Dev Biol
. 2022 Sep;
10:992714.
PMID: 36158200
The ETO-family transcriptional corepressors, including ETO, ETO2, and MTGR1, are all involved in leukemia-causing chromosomal translocations. In every case, an ETO-family corepressor acquires a DNA-binding domain (DBD) to form a...
3.
Zhang F, Zeng Q, Xu H, Xu A, Liu D, Li N, et al.
Cell Discov
. 2021 Oct;
7(1):98.
PMID: 34697290
The amino acid response (AAR) and unfolded protein response (UPR) pathways converge on eIF2α phosphorylation, which is catalyzed by Gcn2 and Perk, respectively, under different stresses. This close interconnection makes...
4.
Liu D, Zhang F, Chen Y, Jin Y, Zhang Y, Chen S, et al.
Cell Discov
. 2020 Oct;
6:72.
PMID: 33088589
Setd2 is the only enzyme that catalyzes histone H3 lysine 36 trimethylation (H3K36me3) on virtually all actively transcribed protein-coding genes, and this mechanism is evolutionarily conserved from yeast to human....
5.
Chen B, Song J, Hu C, Chen S, Zhang Q, Xu C, et al.
Blood
. 2020 Mar;
135(25):2271-2285.
PMID: 32202636
SETD2, the histone H3 lysine 36 methyltransferase, previously identified by us, plays an important role in the pathogenesis of hematologic malignancies, but its role in myelodysplastic syndromes (MDSs) has been...
6.
Zhang M, Liu N, Zhang Y, Rong B, Wang X, Xu C, et al.
Leukemia
. 2019 Feb;
33(7):1822-1827.
PMID: 30755707
No abstract available.
7.
Liu N, Song J, Xie Y, Wang X, Rong B, Man N, et al.
Proc Natl Acad Sci U S A
. 2018 Dec;
116(3):890-899.
PMID: 30593567
The AML1-ETO fusion protein, generated by the t(8;21) chromosomal translocation, is causally involved in nearly 20% of acute myeloid leukemia (AML) cases. In leukemic cells, AML1-ETO resides in and functions...
8.
Zhang Y, Sun J, Xie Y, Zhou Y, Liu P, Song J, et al.
Cell Res
. 2018 Mar;
28(4):476-490.
PMID: 29531312
The histone H3 lysine 36 methyltransferase SETD2 is frequently mutated in various cancers, including leukemia. However, there has not been any functional model to show the contribution of SETD2 in...
9.
Wu J, Wu B, Zhang Y, Xie Y, Huang Q
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2013 Sep;
21(4):999-1004.
PMID: 23998601
This study was aimed to investigate the effect of GATA-2 over-expression on function of mouse fetal liver hematopoietic stem cells. GATA-2 was introduced into mouse fetal liver cells via retrovirus...
10.
Chen J, Zhang Y, Zhang Y, Wei C, Liu X, Zhou N, et al.
Mol Biol Rep
. 2012 Dec;
40(3):2243-52.
PMID: 23203408
Enterotoxigenic Escherichia coli F18 is a major pathogen that causes postweaning diarrhoea and edema disease in piglets. The alpha(1,2)-fucosyltransferase (FUT1) gene has been identified as an ideal candidate gene for...