Chun-Hui Xu
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Explore the profile of Chun-Hui Xu including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
177
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Recent Articles
1.
Yu P, Hou D, Chang B, Liu N, Xu C, Chen X, et al.
Dev Cell
. 2024 May;
59(15):1954-1971.e7.
PMID: 38776924
A significant variation in chromatin accessibility is an epigenetic feature of leukemia. The cause of this variation in leukemia, however, remains elusive. Here, we identify SMARCA5, a core ATPase of...
2.
Xu C, Chen X, Zhu G, Yi H, Chen S, Liu T, et al.
J Microbiol Immunol Infect
. 2023 Dec;
57(1):11-19.
PMID: 38065767
Background: Metagenomic Next-Generation Sequencing (mNGS) is a rapid, non-culture-based, high-throughput technique for pathogen diagnosis. Despite its numerous advantages, only a few studies have investigated its use in patients undergoing allogeneic...
3.
Jin J, Chen B, Deng C, Chen J, Xu F, Tao Y, et al.
Sci Adv
. 2023 Nov;
9(48):eadi7375.
PMID: 38019913
Myelodysplastic syndrome (MDS) is a group of clonal hematopoietic neoplasms originating from hematopoietic stem progenitor cells (HSPCs). We previously identified frequent roundabout guidance receptor 1 () mutations in patients with...
4.
Fei M, Wang Y, Chang B, Xue K, Dong F, Huang D, et al.
Blood
. 2023 Jun;
142(10):903-917.
PMID: 37319434
The bone marrow microenvironment (BMM) can regulate leukemia stem cells (LSCs) via secreted factors. Increasing evidence suggests that dissecting the mechanisms by which the BMM maintains LSCs may lead to...
5.
Jiang Y, Xu C, Zhao Y, Ji Y, Wang X, Liu Y
Eur J Histochem
. 2023 Jan;
67(1).
PMID: 36647631
Vascular endothelial cell (VEC) dysfunction is associated with the development of coronary heart disease (CHD). Long intergenic non-protein coding RNA 926 (LINC00926), a kind of long noncoding RNA (lncRNA), has...
6.
Li X, Wu J, Liu P, Li Z, Wang Y, Chen B, et al.
Leukemia
. 2022 Nov;
37(1):164-177.
PMID: 36352191
The patients with relapsed and refractory diffuse large B-cell lymphoma (DLBCL) have poor prognosis, and a novel and effective therapeutic strategy for these patients is urgently needed. Although ubiquitin-specific protease...
7.
Hu C, Chen B, Li Z, Yang T, Xu C, Yang R, et al.
Cell Res
. 2022 Oct;
32(12):1105-1123.
PMID: 36302855
Aberrant self-renewal of leukemia initiation cells (LICs) drives aggressive acute myeloid leukemia (AML). Here, we report that UHRF1, an epigenetic regulator that recruits DNMT1 to methylate DNA, is highly expressed...
8.
Zhang Y, Wang X, Xu C, Liu N, Zhang L, Zhang Y, et al.
Front Cell Dev Biol
. 2022 Sep;
10:992714.
PMID: 36158200
The ETO-family transcriptional corepressors, including ETO, ETO2, and MTGR1, are all involved in leukemia-causing chromosomal translocations. In every case, an ETO-family corepressor acquires a DNA-binding domain (DBD) to form a...
9.
Ru Y, Dong S, Xu C, Zhao S, Zhang H, Liang H, et al.
Blood Sci
. 2022 Apr;
3(1):6-13.
PMID: 35399204
To understand the behavior and function of bone-marrow mesenchymal cells (BMMCs), we overviewed the morphological presentation of BMMCs in bone-marrow granules (b-BMMCs), isolated BMMCs (i-BMMCs), and BMMCs (c-BMMCs) cultured in...
10.
Zhang F, Zeng Q, Xu H, Xu A, Liu D, Li N, et al.
Cell Discov
. 2021 Oct;
7(1):98.
PMID: 34697290
The amino acid response (AAR) and unfolded protein response (UPR) pathways converge on eIF2α phosphorylation, which is catalyzed by Gcn2 and Perk, respectively, under different stresses. This close interconnection makes...