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Yuan-Hua Chen

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Articles 104
Citations 1547
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Recent Articles
1.
Zhang Z, Yan H, Liu M, Niu F, Yao K, Feng S, et al.
Ecotoxicol Environ Saf . 2025 Jan; 290:117741. PMID: 39818140
Inorganic arsenic is a Class I human Carcinogen. However, the role of chronic inorganic arsenic exposure on prostate cancer metastasis still unclear. This study aimed to investigate the effects and...
2.
Lv Z, Liu C, Wang P, Chen Y
J Lipid Res . 2024 Sep; 65(10):100639. PMID: 39236859
Male obesity is a pandemic health issue and can disrupt testicular steroidogenesis. Here, we explored the mechanism by which a high-fat diet (HFD) induced steroidogenic inhibition. As expected, HFD induced...
3.
Li R, Xu Y, Wen X, Chen Y, Wang P, Zhao J, et al.
Cell Rep . 2024 Jan; 43(2):113708. PMID: 38294902
Organisms sensing environmental cues and internal states and integrating the sensory information to control fecundity are essential for survival and proliferation. The present study finds that a moderate cold temperature...
4.
Jiang P, Lin S, Liu J, Liu Y, Zheng L, Hong Q, et al.
Arch Toxicol . 2023 Aug; 97(11):2929-2941. PMID: 37603095
Maternal lipopolysaccharide (LPS) exposure during pregnancy has been related to IUGR. Here, we explored whether paternal LPS exposure before mating impaired fetal development. All male mice except controls were intraperitoneally...
5.
Lin S, Ye M, Fu Q, Pan C, Liu Y, Zheng L, et al.
FASEB J . 2023 Feb; 37(3):e22820. PMID: 36801982
Epidemiological studies suggest that fetal growth restriction (FGR) caused by gestational cholestasis is associated with elevated serum cholic acid (CA). Here, we explore the mechanism by which CA induces FGR....
6.
Gao X, Lin S, Jiang P, Ye M, Chen W, Hu C, et al.
FASEB J . 2022 May; 36(7):e22388. PMID: 35639049
Epidemiological and animal experimental studies suggest an association between gestational cholestasis and intrauterine growth restriction (IUGR). Here, we explored the mechanism through which gestational cholestasis induced IUGR. To establish gestational...
7.
Gao L, Cui A, Wang J, Chen J, Zhang X, Lin Z, et al.
Environ Sci Pollut Res Int . 2021 Jun; 28(42):60032-60040. PMID: 34155591
Microcystin-leucine arginine (MC-LR) has reproductive and developmental toxicities. Previous studies indicated that gestational exposure to MC-LR induced fetal growth restriction in mice. The aim of this study was to further...
8.
Tong B, Fu L, Hu B, Zhang Z, Tan Z, Li S, et al.
BMC Pulm Med . 2021 May; 21(1):149. PMID: 33952237
Background: Several studies demonstrate that endoplasmic reticulum (ER) stress-mediated epithelial-mesenchymal transition (EMT) is involved in the process of bleomycin (BLM)-induced pulmonary fibrosis. Tauroursodeoxycholic acid (TUDCA), a bile acid with chaperone...
9.
Gao L, Chen J, Li J, Cui A, Zhang W, Li X, et al.
Sci Total Environ . 2021 Apr; 781:146730. PMID: 33798882
Previous studies demonstrated that microcystin-leucine-arginine (MC-LR) disrupted testosterone (T) synthesis, but the underlying mechanisms are not entirely elucidated. This study aims to explore the role of reactive oxygen species (ROS)-mediated...
10.
Ma L, Chen Y, Liu Z, Gao L, Wang B, Fu L, et al.
J Nutr Biochem . 2021 Feb; 91:108601. PMID: 33548476
Vitamin D deficiency has been associated with adverse pregnant outcomes. Several studies investigated the effects of maternal vitamin D3 supplementation on fetal development with inconsistent results. The aim of this...