Yu Muta
Overview
Explore the profile of Yu Muta including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
151
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Recent Articles
1.
Muta Y, Nakanishi Y
Eur J Cell Biol
. 2025 Feb;
104(2):151478.
PMID: 39919450
Colorectal cancer (CRC) organoids provide more accurate and tissue-relevant models compared to conventional two-dimensional cultured cell cultures. Mouse CRC organoids, in particular, offer unique advantages over their human counterparts, as...
2.
Nagao M, Fukuda A, Kashima H, Matsuyama S, Iimori K, Nakayama S, et al.
Eur J Cell Biol
. 2024 Dec;
104(1):151472.
PMID: 39721346
The biliary tract is a ductal network comprising the intrahepatic (IHBDs) and extrahepatic bile duct (EHBDs). Biliary duct disorders include cholangitis, neoplasms, and injury. However, the underlying mechanisms are not...
3.
Hamada K, Nakanishi Y, Muta Y, Omatsu M, Iwane K, Ikeda M, et al.
Cell Mol Gastroenterol Hepatol
. 2024 Dec;
19(3):101435.
PMID: 39631567
Background & Aims: Retinoblastoma-binding protein 9 (RBBP9) was initially reported as cell cycle regulator via RB/E2F. Accumulating evidence has revealed the importance of RBBP9 in physiological and pathological states including...
4.
Kinoshita H, Martinez-Ordonez A, Cid-Diaz T, Han Q, Duran A, Muta Y, et al.
Dev Cell
. 2024 May;
59(15):1972-1987.e8.
PMID: 38815584
The early mechanisms of spontaneous tumor initiation that precede malignancy are largely unknown. We show that reduced aPKC levels correlate with stem cell loss and the induction of revival and...
5.
Ishiguro T, Sugino A, Ishikawa H, Muta Y, Ito T, Yamamoto A, et al.
Gan To Kagaku Ryoho
. 2024 Feb;
50(13):1819-1822.
PMID: 38303218
Cronkhite-Canada syndrome(CCS)is a rare non-inherited disease characterized by gastrointestinal polyposis and ectodermal abnormalities. We report a rare case of CCS associated with gastric cancer and gastric outlet obstruction with a...
6.
Muta Y, Linares J, Martinez-Ordonez A, Duran A, Cid-Diaz T, Kinoshita H, et al.
Nat Commun
. 2023 Dec;
14(1):8075.
PMID: 38092754
The metabolic and signaling pathways regulating aggressive mesenchymal colorectal cancer (CRC) initiation and progression through the serrated route are largely unknown. Although relatively well characterized as BRAF mutant cancers, their...
7.
Mori Y, Chika N, Suzuki O, Matsuyama T, Ito T, Muta Y, et al.
Gan To Kagaku Ryoho
. 2023 Nov;
50(10):1111-1113.
PMID: 38035847
A 47-year-old woman diagnosed with transverse colon cancer with liver, peritoneal, and lymph node metastases was admitted. Modified FOLFOX6(mFOLFOX6)regimen was given as a first line chemotherapy and was followed by...
8.
Omatsu M, Nakanishi Y, Iwane K, Aoyama N, Duran A, Muta Y, et al.
Nat Commun
. 2023 Sep;
14(1):5534.
PMID: 37749092
Mesenchymal activation, characterized by dense stromal infiltration of immune and mesenchymal cells, fuels the aggressiveness of colorectal cancers (CRC), driving progression and metastasis. Targetable molecules in the tumor microenvironment (TME)...
9.
Masuda T, Fukuda A, Yamakawa G, Omatsu M, Namikawa M, Sono M, et al.
J Clin Invest
. 2023 Sep;
133(18).
PMID: 37712427
RECK is downregulated in various human cancers; however, how RECK inactivation affects carcinogenesis remains unclear. We addressed this issue in a pancreatic ductal adenocarcinoma (PDAC) mouse model and found that...
10.
Namikawa M, Fukuda A, Mizukoshi K, Iwane K, Kawai M, Yamakawa G, et al.
J Pathol
. 2023 Jun;
260(4):478-492.
PMID: 37310065
Biliary tract cancer (BTC) has poor prognosis. The Notch receptor is aberrantly expressed in extrahepatic cholangiocarcinoma (eCCA). However, the role of Notch signaling in the initiation and progression of eCCA...