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Yu Fan

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Articles 957
Citations 10661
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Recent Articles
1.
Huang W, Wang T, Chao F, Yang Q, Mixdorf J, Li L, et al.
Mol Pharm . 2025 Mar; PMID: 40059341
Trop2 exhibits significantly elevated expression in numerous solid malignancies, playing a crucial role in tumor advancement, whereas its presence in healthy tissues is minimal. In this study, we investigated Trop2...
2.
Feng C, Fan Y, Gao H, Zhang B, Lu X
Biomark Med . 2025 Mar; 19(6):205-213. PMID: 40035348
Aims: This study mainly explored the regulatory role and mechanism of MCCC2 in GBM. Methods: This study verified the expression in clinical samples and GBM cell lines. CCK-8 and cell...
3.
Fan Y, Yao W, Wang Z, Fan X, Hu S, Wang H, et al.
Plants (Basel) . 2025 Feb; 14(4). PMID: 40006766
In recent years, the impacts of climate change and human activities have intensified the loss and fragmentation of habitats for wild rare Magnoliaceae. Predicting the potential impacts of future climate...
4.
Huang W, Zhang Y, Xiao X, Yang Q, Mixdorf J, Sun X, et al.
Eur J Nucl Med Mol Imaging . 2025 Feb; PMID: 39994021
Purpose: The Trop2-targeting antibody-drug conjugate (ADC) sacituzumab govitecan (Trodelvy) has demonstrated remarkable efficacy in patients with metastatic triple-negative breast cancer (TNBC). ImmunoPET imaging offers a noninvasive method to visualize the...
5.
Palczewski M, Kuschman H, Hoffman B, Kathiresan V, Yang H, Glynn S, et al.
Nat Commun . 2025 Feb; 16(1):1732. PMID: 39966373
DNA methylation at cytosine bases (5-methylcytosine, 5mC) is a heritable epigenetic mark regulating gene expression. While enzymes that metabolize 5mC are well-characterized, endogenous signaling molecules that regulate DNA methylation machinery...
6.
Ye X, Mei L, Gan Z, Wang Z, Sun W, Fan Y, et al.
Plants (Basel) . 2025 Feb; 14(3). PMID: 39942985
Selenium (Se) is an essential trace element for human health, and dietary Se intake is an effective supplement. Rich in nutrients and functional components with potential for Se enrichment, Tartary...
7.
Guo D, Zhang C, Leng C, Fan Y, Wang Y, Chen L, et al.
BMC Palliat Care . 2025 Feb; 24(1):41. PMID: 39939984
Background: Delirium is a common and distressing mental disorder in palliative care. To date, no delirium prediction model is available for thepalliative care population. The research aimed to develop and...
8.
Li Y, Li B, Lai S, Guo X, Fan Y, Wang H, et al.
Arch Oral Biol . 2025 Feb; 172:106188. PMID: 39938345
Objectives: This study aimed to evaluate the biocompatibility, penetrability, sealing ability, and antibacterial properties of iRoot SP compared to AH Plus in root canal filling. Design: Two types of iRoot...
9.
Zhang Y, Hu T, Wang X, Sun N, Cai Q, Kim H, et al.
FASEB J . 2025 Feb; 39(3):e70386. PMID: 39927989
Parental substance abuse increases the risk of neurological and psychiatric disorders in offsprings. However, its underlying mechanism remains elusive. Our previous study demonstrated that long-term exposure to methamphetamine (Meth), a...
10.
Peeney D, Kumar S, Singh T, Liu Y, Jensen S, Chowdhury A, et al.
Transl Oncol . 2025 Feb; 53:102309. PMID: 39904284
Mounting evidence suggests that the tissue inhibitor of metalloproteinases-2 (TIMP2) can reduce tumor burden and metastasis. However, the demonstration of such anti-tumor activity and associated mechanisms using in vivo tumor...