Yu-Mi Lim
Overview
Explore the profile of Yu-Mi Lim including associated specialties, affiliations and a list of published articles.
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22
Citations
633
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Recent Articles
1.
Lee J, Hong S, Kim M, Lim Y, Moon S, Kwon H, et al.
Biochem Biophys Res Commun
. 2024 Sep;
735:150620.
PMID: 39265364
Sodium-dependent glucose cotransporter-2 (SGLT2) inhibitors, antidiabetic drugs that reduce blood sugar levels by inhibiting glucose reabsorption in the renal proximal tubules, also ameliorate nonalcoholic fatty liver disease (NAFLD). This study...
2.
Lee J, Hong S, Kim M, Lim Y, Moon S, Kwon H, et al.
Endocrinol Metab (Seoul)
. 2024 Jan;
39(1):98-108.
PMID: 38171209
Backgruound: Sodium-dependent glucose cotransporter 2 (SGLT2) mediates glucose reabsorption in the renal proximal tubules, and SGLT2 inhibitors are used as therapeutic agents for treating type 2 diabetes mellitus. This study...
3.
Li R, Barros D, Kuah R, Lim Y, Gao A, Beaudry J, et al.
Nat Metab
. 2024 Jan;
6(1):39-49.
PMID: 38167726
Proteins activate small intestinal calcium sensing receptor (CaSR) and/or peptide transporter 1 (PepT1) to increase hormone secretion, but the effect of small intestinal protein sensing and the mechanistic potential of...
4.
Zhang S, Bruce K, Danaei Z, Li R, Barros D, Kuah R, et al.
Cell Metab
. 2023 Apr;
35(5):875-886.e5.
PMID: 37060902
Metformin, the most widely prescribed medication for obesity-associated type 2 diabetes (T2D), lowers plasma glucose levels, food intake, and body weight in rodents and humans, but the mechanistic site(s) of...
5.
Lee S, Lee E, Chae J, Kim J, Lee H, Lim Y, et al.
Nutrients
. 2022 Nov;
14(21).
PMID: 36364945
Akebia quinata, commonly called chocolate vine, has various bioactivities, including antioxidant and anti-obesity properties. However, the anti-obesity effects of bioconverted extracts of A. quinate have not been examined. In this...
6.
Li R, Batchuluun B, Zhang S, Abraham M, Wang B, Lim Y, et al.
iScience
. 2021 Apr;
24(4):102366.
PMID: 33870148
Hypothalamic regulation of lipid and glucose homeostasis is emerging, but whether the dorsal vagal complex (DVC) senses nutrients and regulates hepatic nutrient metabolism remains unclear. Here, we found in rats...
7.
Kim J, Kim S, Kang H, Lee S, Park S, Cho Y, et al.
Nat Metab
. 2021 Mar;
3(3):410-427.
PMID: 33758420
TFEB, a key regulator of lysosomal biogenesis and autophagy, is induced not only by nutritional deficiency but also by organelle stress. Here, we find that Tfeb and its downstream genes...
8.
Waise T, Lim Y, Danaei Z, Zhang S, Lam T
Mol Metab
. 2020 Dec;
44:101132.
PMID: 33264656
Objective: The mechanism of nutrient sensing in the upper small intestine (USI) and ileum that regulates glucose homeostasis remains elusive. Short-term high-fat (HF) feeding increases taurochenodeoxycholic acid (TCDCA; an agonist...
9.
Zhang S, Li R, Lim Y, Batchuluun B, Liu H, Waise T, et al.
Gut
. 2020 Oct;
70(9):1675-1683.
PMID: 33087489
Objective: Conjugated bile acids are metabolised by upper small intestinal microbiota, and serum levels of taurine-conjugated bile acids are elevated and correlated with insulin resistance in people with type 2...
10.
Lim H, Lim Y, Kim K, Jeon Y, Park K, Kim J, et al.
Nat Commun
. 2018 Apr;
9(1):1438.
PMID: 29650965
Autophagy is a critical regulator of cellular homeostasis, dysregulation of which is associated with diverse diseases. Here we show therapeutic effects of a novel autophagy enhancer identified by high-throughput screening...