Yu-Chen Gu
Overview
Explore the profile of Yu-Chen Gu including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
276
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Recent Articles
1.
Li Y, Wang J, Zhang C, Shen Y, Wang H, Ding L, et al.
Oncotarget
. 2016 Aug;
7(37):59287-59298.
PMID: 27494902
Previous studies have indicated that miR-146a-5p acts as an oncogene in several types of cancer, yet a tumor suppressor gene in others. In non-small cell lung cancer (NSCLC), one report...
2.
Tong X, Gu Y, Jiao H, Yu L, Dong S
Zhejiang Da Xue Xue Bao Yi Xue Ban
. 2015 Apr;
44(1):67-73.
PMID: 25851978
Objective: To investigate the effects of inhibiting gap junctional intercellular communication on hypoxia/reoxygenation injury in astrocytes. Methods: Primary cultured cerebral cortical astrocytes of neonate rats were divided into normal control...
3.
Yu B, Tong X, Dong S, Gu Y, Jiao H, Ji J, et al.
Zhonghua Nan Ke Xue
. 2014 Jun;
20(5):400-4.
PMID: 24908728
Objective: To investigate the effects of total flavonoids of Litsea Coreana (TFLC) on the gap junction (GJ) intercellular communication in TM3 testicular Leydig cells and whether TFLC can reduce the...
4.
Gu Y, Rao M, Vemuri M
J Stem Cells
. 2010 Mar;
4(2):95-103.
PMID: 20232595
Human umbilical cord blood (UCB) is a valuable alternative source of ethically acceptable, clinically competent stem cells that is most likely closest to embryonic stem cells. Development of reliable methods...
5.
Peranteau W, Heaton T, Gu Y, Volk S, Bauer T, Alcorn K, et al.
Biol Blood Marrow Transplant
. 2009 Feb;
15(3):293-305.
PMID: 19203720
In the murine model, in utero hematopoietic cell transplantation (IUHCT) has been shown to achieve low levels of allogeneic chimerism and associated donor-specific tolerance permitting minimal conditioning postnatal hematopoietic stem...
6.
Bauer Jr T, Allen J, Hai M, Tuschong L, Khan I, Olson E, et al.
Nat Med
. 2007 Dec;
14(1):93-7.
PMID: 18157138
Recent successes in treating genetic immunodeficiencies have demonstrated the therapeutic potential of stem cell gene therapy. However, the use of gammaretroviral vectors in these trials led to insertional activation of...
7.
Bauer Jr T, Hai M, Tuschong L, Burkholder T, Gu Y, Sokolic R, et al.
Blood
. 2006 Jul;
108(10):3313-20.
PMID: 16868255
Canine leukocyte adhesion deficiency (CLAD) represents the canine counter-part of the human disease leukocyte adhesion deficiency (LAD). Defects in the leukocyte integrin CD18 adhesion molecule in both CLAD and LAD...
8.
Sokolic R, Bauer T, Gu Y, Hai M, Tuschong L, Burkholder T, et al.
Biol Blood Marrow Transplant
. 2005 Sep;
11(10):755-63.
PMID: 16182176
Leukocyte adhesion deficiency (LAD)-1, a primary immunodeficiency disease caused by molecular defects in the leukocyte integrin CD18 molecule, is characterized by recurrent, life-threatening bacterial infections. Myeloablative hematopoietic stem cell transplantation...
9.
Bauer Jr T, Gu Y, Tuschong L, Burkholder T, Bacher J, Starost M, et al.
Exp Hematol
. 2005 May;
33(6):706-12.
PMID: 15911095
Objective: The aim of this study was to test a nonmyeloablative hematopoietic stem cell transplant regimen applicable to children with leukocyte adhesion deficiency (LAD) who have a histocompatible sibling donor...
10.
Gu Y, Bauer Jr T, Ackermann M, Smith C, Kehrli Jr M, Starost M, et al.
Comp Med
. 2004 Sep;
54(4):363-72.
PMID: 15357315
This review highlights the genotype-phenotype relationship of the genetic immunodeficiency disease leukocyte adhesion deficiency (LAD) in humans, dogs, cattle, and mice, and provides assessment of the opportunities that each animal...