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Yousef Al-Abed

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Articles 160
Citations 7303
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Recent Articles
1.
Palandira S, Falvey A, Carrion J, Zeng Q, Chaudhry S, Grossman K, et al.
bioRxiv . 2024 Sep; PMID: 39282308
Background: Acute liver injury (ALI) that progresses into acute liver failure (ALF) is a life-threatening condition with an increasing incidence and associated costs. Acetaminophen (N-acetyl-p-aminophenol, APAP) overdosing is among the...
2.
Li C, Ajmal E, Alok K, Powell K, Wadolowski S, Tambo W, et al.
Biol Sex Differ . 2024 May; 15(1):44. PMID: 38816868
Background: The outcomes of traumatic brain injury (TBI) exhibit variance contingent upon biological sex. Although female sex hormones exert neuroprotective effects, the administration of estrogen and progesterone has not yielded...
3.
Zafeiropoulos S, Ahmed U, Bekiaridou A, Jayaprakash N, Mughrabi I, Saleknezhad N, et al.
Circ Res . 2024 May; 135(1):41-56. PMID: 38712557
Background: Inflammation is pathogenically implicated in pulmonary arterial hypertension; however, it has not been adequately targeted therapeutically. We investigated whether neuromodulation of an anti-inflammatory neuroimmune pathway involving the splenic nerve...
4.
Kurata-Sato I, Mughrabi I, Rana M, Gerber M, Al-Abed Y, Sherry B, et al.
Sci Adv . 2024 Apr; 10(17):eadn3760. PMID: 38669336
Acetylcholine is produced in the spleen in response to vagus nerve activation; however, the effects on antibody production have been largely unexplored. Here, we use a chronic vagus nerve stimulation...
5.
Bloom J, Pantouris G, He M, Aljabari B, Mishra L, Manjula R, et al.
Mol Med . 2024 Mar; 30(1):43. PMID: 38539088
Background: Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine that has been implicated in multiple inflammatory and non-inflammatory diseases, including liver injury induced by acetaminophen (APAP) overdose. Multiple small...
6.
Powell K, Wadolowski S, Tambo W, Strohl J, Kim D, Turpin J, et al.
bioRxiv . 2024 Feb; PMID: 38405863
Aims: This study aims to elucidate the underlying mechanisms of diving reflex, a powerful endogenous mechanism supporting underwater mammalian survival. Antioxidative responses, observed in marine mammals, may be contributing factors....
7.
Mughrabi I, Gerber M, Jayaprakash N, Palandira S, Al-Abed Y, Datta-Chaudhuri T, et al.
J Neuroinflammation . 2023 Oct; 20(1):236. PMID: 37848937
Background: The noradrenergic innervation of the spleen is implicated in the autonomic control of inflammation and has been the target of neurostimulation therapies for inflammatory diseases. However, there is no...
8.
Chang E, Gabalski A, Huerta T, Datta-Chaudhuri T, Zanos T, Zanos S, et al.
Bioelectron Med . 2023 Oct; 9(1):21. PMID: 37794457
The emerging field of bioelectronic medicine (BEM) is poised to make a significant impact on the treatment of several neurological and inflammatory disorders. With several BEM therapies being recently approved...
9.
Song W, Jayaprakash N, Saleknezhad N, Puleo C, Al-Abed Y, Martin J, et al.
Neuromodulation . 2023 Aug; 27(4):614-624. PMID: 37530695
Objectives: Low-intensity, focused ultrasound (FUS) is an emerging noninvasive neuromodulation approach, with improved spatial and temporal resolution and penetration depth compared to other noninvasive electrical stimulation strategies. FUS has been...
10.
Choudhary R, Shoaib M, Hayashida K, Yin T, Miyara S, dAbramo C, et al.
Cells . 2023 Jun; 12(11). PMID: 37296668
Background: Cardiac arrest (CA) can lead to neuronal degeneration and death through various pathways, including oxidative, inflammatory, and metabolic stress. However, current neuroprotective drug therapies will typically target only one...