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Young Yiul Lee

Explore the profile of Young Yiul Lee including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 359
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Recent Articles
11.
Choi J, Yoon J, Won Y, Park B, Lee Y
APMIS . 2012 Jun; 120(7):597-604. PMID: 22716215
Autophagy is a conserved catabolic process that degrades cytoplasmic proteins and organelles for recycling. The role of autophagy in tumorigenesis is controversial because autophagy can be either protective or damaging...
12.
Yoon J, Won Y, Kim S, Oh S, Kim E, Kim B, et al.
Invest New Drugs . 2012 Apr; 30(6):2284-93. PMID: 22526834
Substituted 2-pyrones are important structural sub-units present in a number of natural products having broad range of biological activity. However, little is known about the anti-cancer effect of 2-pyrone derivatives...
13.
Yoon C, Kim M, Lee H, Kim R, Lim E, Yoo K, et al.
J Biol Chem . 2012 Apr; 287(23):19516-27. PMID: 22511756
The prognosis of breast cancer patients is related to the degree of metastasis. However, the mechanisms by which epithelial tumor cells escape from the primary tumor and colonize at a...
14.
Lim Y, Lee Y, Kim J, Shin J, Lee J, Kim K, et al.
Korean J Hematol . 2010 Dec; 45(2):136-8. PMID: 21120194
Essential thrombocythemia (ET) is a chronic myeloproliferative disorder with a prolonged clinical course. Since this disorder is considered to be at increased risk of thromboembolism, therapy is mainly focused on...
15.
Kim J, Park H, Yoon J, Kim S, Kim E, Song S, et al.
Oncol Rep . 2010 Apr; 23(5):1369-74. PMID: 20372853
Leptin acts as a growth factor in normal cells as well as in various types of cancer cells. We investigated the effects of leptin on human acute myelogenous leukemia (AML)...
16.
Choi J, Song Y, Yoon J, Song K, Lee Y
APMIS . 2010 Feb; 118(3):196-202. PMID: 20132185
The enhancer of zeste homolog 2 (EZH2), a member of the polycomb group of proteins, plays an important role in cell proliferation and cell cycle regulation. EZH2 is overexpressed in...
17.
Park B, Kim W, Eom H, Kim J, Lee Y, Oh S, et al.
Invest New Drugs . 2009 Sep; 29(1):154-60. PMID: 19756371
Background: We investigated response rates to and toxicities of gemcitabine, ifosfamide, dexamethasone, and oxaliplatin (GIDOX) for the treatment of relapsed or refractory aggressive B-cell non-Hodgkin lymphoma (NHL). Patients And Methods:...
18.
Koh Y, Park J, Bae E, Ahn K, Kim I, Bang S, et al.
Int J Hematol . 2009 Jun; 90(1):1-5. PMID: 19484332
Mutations of nucleophosmin gene (NPM1) are known to be related to good prognosis in AML patients lacking FLT3 internal tandem duplication (FLT3-ITD). Recently, NPM1 mutations other than type A were...
19.
Koh Y, Park J, Ahn K, Kim I, Bang S, Lee J, et al.
Ann Hematol . 2009 Mar; 88(11):1089-97. PMID: 19296110
Impact of FLT3 receptor tyrosine kinase activation via internal tandem duplication (ITD) of the juxtamembrane region on outcome of acute myeloid leukemia (AML) is still controversial. Recent researches reveal a...
20.
Kim J, Park H, Yoon J, Kim S, Kim E, Ahn K, et al.
Int J Oncol . 2008 Aug; 33(3):493-501. PMID: 18695878
This study investigated whether advanced glycation end products (AGE) and RAGE (receptor for AGE) are involved in the proliferation of leukemia cells. AGE strongly induced the proliferation of primary acute...