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Young Ho Koh

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Articles 105
Citations 7367
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Recent Articles
1.
Nguyen M, Nguyen T, Kim Y, Koh Y
NPJ Sci Food . 2025 Feb; 9(1):27. PMID: 40000656
Metabolic disorders encompass various dysregulations, such as dyslipidemia, hypertension, central obesity, atherogenic hyperlipidemia, and insulin resistance. Dyslipidemia refers to elevated levels of total cholesterol, low-density lipoprotein cholesterol, and triglycerides, along...
2.
Oh S, Sohn H, Seo J, Kang E, Park J, Moon S, et al.
Aging Dis . 2025 Feb; PMID: 39965244
Brain diseases complexity have necessitated advanced research platforms for better understanding, treatment, and prevention strategies. However, existing brain disease registries face limitations such as incomplete variable sets, lack of standardization,...
3.
Nguyen T, Jang B, Kim S, Kang S, Kim K, Kim Y, et al.
Nutrients . 2025 Feb; 17(3). PMID: 39940275
Objectives: The immune-enhancing properties of steamed mature silkworm, known as HongJam (HJ), were investigated using human interleukin-2-independent Natural Killer 92 (NK92-MI) cells and a cyclophosphamide intraperitoneal injection-induced immunosuppressed mice model...
4.
Chung H, Shin J, Kim M, Ahn S, Koh Y, Eom S, et al.
Food Chem . 2025 Jan; 471:142780. PMID: 39793364
Effects of puffing and extraction method on physical and biological efficacy of bitter melon was investigated. Puffing increased the Maillard reaction products, extraction yield, total phenolic and total flavonoid contents....
5.
Phan T, Jang B, Kang S, Seo J, Kim S, Kim K, et al.
Nutrients . 2024 Nov; 16(22). PMID: 39599718
Objectives: The unknown immune-enhancing effects of steamed mature silkworms ( L.), known as HongJam (HJ), were investigated. Methods: Supercritical fluid extracts from the White Jade variety of HJ (WJ-SCEs) were...
6.
Yoon G, Kam M, Koh Y, Jo C
PLoS One . 2024 Nov; 19(11):e0313507. PMID: 39536002
Alzheimer's disease (AD) is characterized by cognitive decline and memory loss, involving mechanisms such as tau hyperphosphorylation and mitochondrial dysfunction. Increasing evidence suggests that age-related alterations in metabolite levels are...
7.
Lee C, Chang M, Koh Y, Pack S, Seo M, Cha H, et al.
J Hazard Mater . 2024 Nov; 480:136319. PMID: 39488980
Airborne particulate matter less than 10 µm in diameter (PM10) is recognized as a significant environmental risk factor for hemorrhagic stroke (HS), as evidenced by epidemiological studies that link PM10...
8.
Chang M, Park J, Lee H, Choi J, Koh Y
Biomedicines . 2024 Jun; 12(6). PMID: 38927430
Abnormal aggregation of α-synuclein is the hallmark of neurodegenerative diseases, classified as α-synucleinopathies, primarily occurring sporadically. Their onset is associated with an interaction between genetic susceptibility and environmental factors such...
9.
Kam M, Park J, Yun G, Sohn H, Park J, Choi J, et al.
Mol Neurobiol . 2024 Apr; 61(11):9633-9645. PMID: 38671330
Intra-neuronal accumulation of hyper-phosphorylated tau as neurofibrillary tangles (NFT) is a hallmark of Alzheimer's disease (AD). To prevent the aggregation of phosphorylated tau in neurons, decreasing the phosphorylated tau protein...
10.
Baek D, Lee K, Sohn H, Park J, Lee H, Bayarsaikhan G, et al.
Stem Cell Res . 2024 Mar; 76:103358. PMID: 38447455
Parkinson's disease is a degenerative brain disorder characterized by dopamine neuronal degeneration and dopamine transporter loss. In this study, we generated an induced pluripotent stem cell (iPSC) line, KNIHi001-A, from...