Yoshiyuki Goto
Overview
Explore the profile of Yoshiyuki Goto including associated specialties, affiliations and a list of published articles.
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42
Citations
1659
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Recent Articles
1.
Suzuki K, Goto Y, Otomo A, Shimizu K, Abe S, Moriyama K, et al.
Nat Struct Mol Biol
. 2024 Nov;
PMID: 39572733
Vancomycin-resistant Enterococcus faecium (VRE) is a major cause of nosocomial infections, particularly endocarditis and sepsis. With the diminishing effectiveness of antibiotics against VRE, new antimicrobial agents are urgently needed. Our...
2.
Hayashi K, Uchida R, Horiba T, Kawaguchi T, Gomi K, Goto Y
Biosci Microbiota Food Health
. 2024 Jul;
43(3):275-281.
PMID: 38966053
The short-chain fatty acids responsible for gut homeostasis are volatile fatty acids produced by commensal bacteria in the gut as fermentation products from undigested food components. Among the short-chain fatty...
3.
Kurihara S, Suzuki K, Yokota M, Ito T, Hayashi Y, Kikuchi R, et al.
Biomolecules
. 2024 Jan;
14(1).
PMID: 38254689
Oral tolerance has been defined as the specific suppression of immune responses to an antigen by prior oral administration of the antigen. It has been thought to serve to suppress...
4.
McCuaig B, Goto Y
Int J Mol Sci
. 2023 Nov;
24(21).
PMID: 37958628
The gut microbiome is intimately intertwined with the host immune system, having effects on the systemic immune system. Dysbiosis of the gut microbiome has been linked not only to gastrointestinal...
5.
Kamioka M, Goto Y, Nakamura K, Yokoi Y, Sugimoto R, Ohira S, et al.
Proc Natl Acad Sci U S A
. 2022 Jan;
119(3).
PMID: 35027453
Paneth cells are intestinal epithelial cells that release antimicrobial peptides, such as α-defensin as part of host defense. Together with mesenchymal cells, Paneth cells provide niche factors for epithelial stem...
6.
Goto Y
Cell Host Microbe
. 2022 Jan;
30(1):3-5.
PMID: 35026134
Metabolites derived from symbionts have the potential to regulate host pathophysiological conditions, especially in the gut. In a recent issue of Nature, Oh et al. clarify unique molecular structures of...
7.
Dainichi T, Kabashima K, Ivanov I, Goto Y
Front Immunol
. 2021 Oct;
12:770847.
PMID: 34621281
No abstract available.
8.
Shimizu K, Seiki I, Goto Y, Murata T
Antibiotics (Basel)
. 2021 Mar;
10(2).
PMID: 33670214
The intestinal pH can greatly influence the stability and absorption of oral drugs. Therefore, knowledge of intestinal pH is necessary to understand the conditions for drug delivery. This has previously...
9.
Goto Y
Nihon Saikingaku Zasshi
. 2020 Dec;
75(2):185-194.
PMID: 33361654
Countless numbers of bacteria inhabit the intestinal tract. One of the important functions of gut microbiota is the "colonization resistance" against infection by pathogenic microorganisms. However, detailed mechanism of the...
10.
Yahiro K, Ogura K, Goto Y, Iyoda S, Kobayashi T, Takeuchi H, et al.
Sci Rep
. 2020 Nov;
10(1):18943.
PMID: 33144618
Shiga-toxigenic Escherichia coli (STEC) infection causes severe bloody diarrhea, renal failure, and hemolytic uremic syndrome. Recent studies showed global increases in Locus for Enterocyte Effacement (LEE)-negative STEC infection. Some LEE-negative...