Yoshitaka Shirasaki
Overview
Explore the profile of Yoshitaka Shirasaki including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
598
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Recent Articles
1.
Isozaki A, Kita K, Tiffany Ishii N, Oka Y, Herbig M, Yamagishi M, et al.
Cytometry A
. 2025 Feb;
PMID: 39982013
T cells play a pivotal role in the immune system's response to various conditions. They are activated by antigen-presenting cells (APCs) via T-cell surface receptors, resulting in cytokine production and...
2.
Yamagishi M, Miyata K, Kamatani T, Kabata H, Baba R, Tanaka Y, et al.
iScience
. 2024 May;
27(6):109840.
PMID: 38779479
Quantification of cytokine secretion has facilitated advances in the field of immunology, yet the dynamic and varied secretion profiles of individual cells, particularly those obtained from limited human samples, remain...
3.
Baba R, Kabata H, Shirasaki Y, Kamatani T, Yamagishi M, Irie M, et al.
J Allergy Clin Immunol Glob
. 2023 Oct;
1(4):299-304.
PMID: 37779537
Background: Group 2 innate lymphoid cells (ILC2s) produce type 2 cytokines by stimulation with epithelial cell-derived cytokines and are implicated in the pathogenesis of various allergic diseases, including asthma. However,...
4.
Tanaka Y, Yamagishi M, Motomura Y, Kamatani T, Oguchi Y, Suzuki N, et al.
Commun Biol
. 2023 Sep;
6(1):915.
PMID: 37673922
The decision of whether cells are activated or not is controlled through dynamic intracellular molecular networks. However, the low population of cells during the transition state of activation renders the...
5.
Irie M, Kabata H, Sasahara K, Kurihara M, Shirasaki Y, Kamatani T, et al.
Cell Rep
. 2023 Jun;
42(6):112610.
PMID: 37294636
Group 2 innate lymphoid cells (ILC2s) produce large amounts of type 2 cytokines including interleukin-5 (IL-5) and IL-13 in response to various stimuli, causing allergic and eosinophilic diseases. However, the...
6.
Fujimoto K, Nakajima A, Hori S, Tanaka Y, Shirasaki Y, Uemura S, et al.
Sci Rep
. 2022 Nov;
12(1):18313.
PMID: 36333354
Even though the mother and the fetus of placental mammals are immunologically non-self with respect to one other, mutual exchange of small numbers of cells between them is known to...
7.
Matsui Y, Takemura N, Shirasaki Y, Takahama M, Noguchi Y, Ikoma K, et al.
Int Immunol
. 2022 Jun;
34(10):505-518.
PMID: 35759801
Nod-like receptor family pyrin domain-containing 3 (NLRP3) is a cytosolic innate immune receptor that senses organelle dysfunction induced by various stimuli, such as infectious, environmental, metabolic and drug stresses. Upon...
8.
Murai S, Shirasaki Y, Nakano H
Methods Mol Biol
. 2021 May;
2274:353-363.
PMID: 34050485
Necroptosis is a regulated form of necrosis that depends on receptor-interacting protein kinase (RIPK)3 and mixed lineage kinase domain-like protein (MLKL). Necroptotic cells release a variety of cellular and nuclear...
9.
Yamagishi M, Shirasaki Y
Methods Mol Biol
. 2021 May;
2274:337-352.
PMID: 34050484
The present protocol introduces a live-cell imaging of secretion activity (LCI-S) that is useful to visualize the real-time release of molecules from individual cells using an immunoassay coupled with total...
10.
Nitta N, Iino T, Isozaki A, Yamagishi M, Kitahama Y, Sakuma S, et al.
Nat Commun
. 2020 Jul;
11(1):3452.
PMID: 32651381
The advent of image-activated cell sorting and imaging-based cell picking has advanced our knowledge and exploitation of biological systems in the last decade. Unfortunately, they generally rely on fluorescent labeling...