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Yoshiro Ishimaru

Explore the profile of Yoshiro Ishimaru including associated specialties, affiliations and a list of published articles. Areas
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Articles 46
Citations 950
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Recent Articles
1.
Itoigawa A, Toda Y, Kuraku S, Ishimaru Y
Curr Biol . 2024 Apr; 34(7):R271-R272. PMID: 38593768
Taste is a sense that detects information about nutrients and toxins in foods. Of the five basic taste qualities, bitterness is associated with the detection of potentially harmful substances like...
2.
Nishihara H, Toda Y, Kuramoto T, Kamohara K, Goto A, Hoshino K, et al.
Nat Ecol Evol . 2023 Dec; 8(1):111-120. PMID: 38093021
Taste is a vital chemical sense for feeding behaviour. In mammals, the umami and sweet taste receptors comprise three members of the taste receptor type 1 (T1R/TAS1R) family: T1R1, T1R2...
3.
Toda Y, Hayakawa T, Itoigawa A, Kurihara Y, Nakagita T, Hayashi M, et al.
Curr Biol . 2021 Oct; 31(20):4675-4676. PMID: 34699792
No abstract available.
4.
Shimizu T, Kubozono T, Asaoka R, Toda Y, Ishimaru Y
Biochem Biophys Rep . 2021 Sep; 28:101123. PMID: 34504956
Bitter taste perception is mediated by a family of G protein-coupled receptors (T2Rs) in vertebrates. Common carp (), which has experienced an additional round of whole genome duplication during the...
5.
Toda Y, Hayakawa T, Itoigawa A, Kurihara Y, Nakagita T, Hayashi M, et al.
Curr Biol . 2021 Aug; 31(20):4641-4649.e5. PMID: 34450087
Taste perception plays an essential role in food selection. Umami (savory) tastes are sensed by a taste receptor complex, T1R1/T1R3, that detects proteinogenic amino acids. High sensitivity to l-glutamate (l-Glu)...
6.
Kasahara Y, Narukawa M, Ishimaru Y, Kanda S, Umatani C, Takayama Y, et al.
J Physiol Sci . 2021 Aug; 71(1):23. PMID: 34429071
"Salty taste" sensation is evoked when sodium and chloride ions are present together in the oral cavity. The presence of an epithelial cation channel that receives Na has previously been...
7.
Toda Y, Ko M, Liang Q, Miller E, Rico-Guevara A, Nakagita T, et al.
Science . 2021 Jul; 373(6551):226-231. PMID: 34244416
Early events in the evolutionary history of a clade can shape the sensory systems of descendant lineages. Although the avian ancestor may not have had a sweet receptor, the widespread...
8.
Toda Y, Nakagita T, Hirokawa T, Yamashita Y, Nakajima A, Narukawa M, et al.
Sci Rep . 2018 Aug; 8(1):11796. PMID: 30087430
Taste is a vital sensation for vertebrates, enabling the detection of nutritionally important substances or potential toxins. A heteromeric complex of two class C GPCRs, T1R1 and T1R3, was identified...
9.
Takuma A, Abe A, Saito Y, Nito C, Ueda M, Ishimaru Y, et al.
Int J Mol Sci . 2017 Nov; 18(11). PMID: 29113076
Given the abundance of stroke patients and deaths from stroke worldwide, many studies concerning the aftermath of stroke are being carried out. To reveal the precise effect of ischemic infarction,...
10.
Maeda N, Narukawa M, Ishimaru Y, Yamamoto K, Misaka T, Abe K
Neurosci Lett . 2017 Apr; 648:53-58. PMID: 28359935
The connections between taste receptor cells (TRCs) and innervating gustatory neurons are formed in a mutually dependent manner during development. To investigate whether a change in the ratio of cell...