Yoshiki Sasai
Overview
Explore the profile of Yoshiki Sasai including associated specialties, affiliations and a list of published articles.
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Articles
107
Citations
10031
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Recent Articles
1.
Kuwahara A, Yamasaki S, Mandai M, Watari K, Matsushita K, Fujiwara M, et al.
Sci Rep
. 2020 Feb;
10(1):2237.
PMID: 32024912
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
2.
Kuwahara A, Yamasaki S, Mandai M, Watari K, Matsushita K, Fujiwara M, et al.
Sci Rep
. 2019 Dec;
9(1):18936.
PMID: 31831759
A three-dimensional retinal tissue (3D-retina) is a promising graft source for retinal transplantation therapy. We previously demonstrated that embryonic stem cells (ESCs) can generate 3D-retina in vitro using a self-organizing...
3.
Takata N, Abbey D, Fiore L, Acosta S, Feng R, Gil H, et al.
Cell Rep
. 2017 Nov;
21(6):1534-1549.
PMID: 29117559
Recent advances in self-organizing, 3-dimensional tissue cultures of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) provided an in vitro model that recapitulates many aspects of the in ...
4.
Takata N, Sakakura E, Eiraku M, Kasukawa T, Sasai Y
Nat Commun
. 2017 Nov;
8(1):1339.
PMID: 29109536
The neuroectoderm is patterned along a rostral-caudal axis in response to localized factors in the embryo, but exactly how these factors act as positional information for this patterning is not...
5.
Ohgushi M, Minaguchi M, Eiraku M, Sasai Y
Stem Cell Reports
. 2017 Jun;
9(1):58-66.
PMID: 28579391
Pluripotent stem cells can undergo repeated self-renewal while retaining genetic integrity, but they occasionally acquire aneuploidy during long-term culture, which is a practical obstacle for medical applications of human pluripotent...
6.
Shiraishi A, Muguruma K, Sasai Y
Development
. 2017 Feb;
144(7):1211-1220.
PMID: 28219951
The thalamus is a diencephalic structure that plays crucial roles in relaying and modulating sensory and motor information to the neocortex. The thalamus develops in the dorsal part of the...
7.
Ishida Y, Kawakami H, Kitajima H, Nishiyama A, Sasai Y, Inoue H, et al.
Cell Rep
. 2017 Jan;
18(4):1075-1076.
PMID: 28122232
No abstract available.
8.
Ishida Y, Kawakami H, Kitajima H, Nishiyama A, Sasai Y, Inoue H, et al.
Cell Rep
. 2016 Nov;
17(6):1482-1490.
PMID: 27806289
Spinocerebellar ataxia type 6 (SCA6) is a dominantly inherited neurodegenerative disease characterized by loss of Purkinje cells in the cerebellum. SCA6 is caused by CAG trinucleotide repeat expansion in CACNA1A,...
9.
Hasegawa Y, Takata N, Okuda S, Kawada M, Eiraku M, Sasai Y
Development
. 2016 Sep;
143(21):3895-3906.
PMID: 27633992
We previously demonstrated that mouse embryonic stem cell (mESC)-derived retinal epithelium self-forms an optic cup-like structure. In the developing retina, the dorsal and ventral sides differ in terms of local...
10.
Takata N, Sakakura E, Sasai Y
In Vitro Cell Dev Biol Anim
. 2016 Mar;
52(5):607-15.
PMID: 26956358
Insulin-like growth factors (IGFs) are involved in growth and tissue development, including diseases such as type-2 diabetes and cancers. However, their roles in lineage specification, especially in early mammalian neural...