Yoshiaki Sugita
Overview
Explore the profile of Yoshiaki Sugita including associated specialties, affiliations and a list of published articles.
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Articles
73
Citations
305
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Recent Articles
1.
Kamauchi H, Tanaka M, Koyama K, Kiba Y, Kitamura M, Sugita Y
J Nat Med
. 2024 Nov;
79(1):226-232.
PMID: 39514057
Two novel aromatic polyketides, penicanesins J and K (1, 2), were isolated from the marine-derived fungus Didymella aeria, along with the known compound integrastatin B (3). The structures of the...
2.
Kamauchi H, Goto M, Sugita Y
J Org Chem
. 2024 Jun;
89(12):8960-8969.
PMID: 38860649
The synthesis of daldinans B and E ( and ), 3-phenyl isoindolinones isolated from , was achieved. The conformational properties of these isoindolinones were examined using their derivatives, revealing the...
3.
Kobayashi T, Sakamoto A, Hisano T, Kashiwagi K, Igarashi K, Takao K, et al.
Sci Rep
. 2024 Mar;
14(1):7566.
PMID: 38555406
An extreme thermophilic bacterium, Thermus thermophilus produces more than 20 unusual polyamines, but their biosynthetic pathways, including homospermidine, are not yet fully understood. Two types of homospermidine synthases have been...
4.
Takao K, Kubota Y, Kurosaki K, Kamauchi H, Uesawa Y, Sugita Y
Chem Pharm Bull (Tokyo)
. 2024 Jan;
72(1):109-120.
PMID: 38267058
A series of 2-azolylmethylene-3-(2H)-benzofuranone derivatives, 2-indolylmethylene-3-(2H)-benzofuranone and 2-pyrrolylmethylene-3-(2H)-benzofuranone derivatives, were synthesized, and their monoamine oxidase (MAO) A and B inhibitory activities were evaluated. Compounds 1b, 3b, 6b, 7b, and 10b...
5.
Kamauchi H, Tanaka M, Suzuki M, Furukawa M, Ikeda A, Sasho C, et al.
Chem Pharm Bull (Tokyo)
. 2024 Jan;
72(1):98-101.
PMID: 38233138
A novel tricyclic polyketide, curvulanone (1), was isolated from the marine-derived fungus Curvularia aeria. The structure of 1 was determined by NMR and single-crystal X-ray crystallography. 1 had a cyclopentabenzopyranone...
6.
Kamauchi H, Takanashi A, Suzuki M, Izumi K, Takao K, Sugita Y
Chem Pharm Bull (Tokyo)
. 2024 Jan;
72(1):56-60.
PMID: 38171905
Twenty natural-product-like 2,8-dioxabicyclo[3.3.1]nonane derivatives were synthesized and their neuroprotective activities were tested using human monoamine oxidases (MAO) A and B and acetyl and butyryl cholinesterases (ChE). Compound 1s showed inhibitory...
7.
Abe T, Sakagami H, Amano S, Uota S, Bandow K, Uesawa Y, et al.
Medicines (Basel)
. 2023 Jul;
10(7).
PMID: 37505064
Many anti-cancer drugs used in clinical practice cause adverse events such as oral mucositis, neurotoxicity, and extravascular leakage. We have reported that two 3-styrylchromone derivatives, 7-methoxy-3-[(1)-2-phenylethenyl]-4-1-benzopyran-4-one (Compound ) and 3-[(1)-2-(4-hydroxyphenyl)ethenyl]-7-methoxy-4-1-benzopyran-4-one...
8.
Tagawa Y, Sakagami H, Tanuma S, Amano S, Uota S, Bandow K, et al.
Anticancer Res
. 2023 Jul;
43(8):3429-3439.
PMID: 37500171
Background/aim: Hyperthermia (HT), combined with chemotherapy, has been used to treat various types of cancer. This study aimed to investigate the HT-sensitivity of malignant and non-malignant cells, and then evaluate...
9.
Kamauchi H, Hirata M, Takao K, Sugita Y
ACS Omega
. 2022 Nov;
7(45):41804-41814.
PMID: 36406553
The first total synthesis of isoindolinone (±)-entonalactam A (), originally obtained from the fungus sp., was achieved in 14 steps from commercially available 5-bromovanillin via benzophenone intermediates. Isoindolinone, phthalide, and...
10.
Kamauchi H, Furukawa M, Kiba Y, Kitamura M, Usui K, Katakura M, et al.
J Antibiot (Tokyo)
. 2022 Jul;
75(9):530-533.
PMID: 35859164
Cell adhesion plays a crucial role in candidiasis through invasion of the human body and obtaining resistance to drugs by forming biofilms. Cell adhesion thus is a critical target for...