Yosef Buganim
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Explore the profile of Yosef Buganim including associated specialties, affiliations and a list of published articles.
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53
Citations
2394
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Recent Articles
11.
Stepanenko N, Wolk O, Bianchi E, Wright G, Schachter-Safrai N, Makedonski K, et al.
Front Cell Dev Biol
. 2022 Apr;
10:824629.
PMID: 35478965
Combined hormone drugs are the basis for orally administered contraception. However, they are associated with severe side effects that are even more impactful for women in developing countries, where resources...
12.
Kaduri M, Sela M, Kagan S, Poley M, Abumanhal-Masarweh H, Mora-Raimundo P, et al.
Sci Adv
. 2021 Oct;
7(41):eabj5435.
PMID: 34613777
Neurons within the tumor microenvironment promote cancer progression; thus, their local targeting has potential clinical benefits. We designed PEGylated lipid nanoparticles loaded with a non-opioid analgesic, bupivacaine, to target neurons...
13.
Ankawa R, Goldberger N, Yosefzon Y, Koren E, Yusupova M, Rosner D, et al.
Dev Cell
. 2021 Jul;
56(13):1900-1916.e5.
PMID: 34197726
Stem cells (SCs) play a key role in homeostasis and repair. While many studies have focused on SC self-renewal and differentiation, little is known regarding the molecular mechanism regulating SC...
14.
Kolb T, Khalid U, Simovic M, Ratnaparkhe M, Wong J, Jauch A, et al.
Genes Chromosomes Cancer
. 2020 Aug;
60(5):303-313.
PMID: 32734664
In vitro assays for clustered DNA lesions will facilitate the analysis of the mechanisms underlying complex genome rearrangements such as chromothripsis, including the recruitment of repair factors to sites of...
15.
Seranova E, Palhegyi A, Verma S, Dimova S, Lasry R, Naama M, et al.
J Mol Biol
. 2020 Feb;
432(8):2754-2798.
PMID: 32044344
Autophagy is an intracellular degradation process that is essential for cellular survival, tissue homeostasis, and human health. The housekeeping functions of autophagy in mediating the clearance of aggregation-prone proteins and...
16.
Brill-Karniely Y, Dror D, Duanis-Assaf T, Goldstein Y, Schwob O, Millo T, et al.
Sci Adv
. 2020 Jan;
6(3):eaax2861.
PMID: 31998832
The malignancy potential is correlated with the mechanical deformability of the cancer cells. However, mechanical tests for clinical applications are limited. We present here a Triangular Correlation (TrC) between cell...
17.
Benchetrit H, Jaber M, Zayat V, Sebban S, Pushett A, Makedonski K, et al.
Cell Stem Cell
. 2019 Apr;
24(6):983-994.e7.
PMID: 31031139
Following fertilization, totipotent cells undergo asymmetric cell divisions, resulting in three distinct cell types in the late pre-implantation blastocyst: epiblast (Epi), primitive endoderm (PrE), and trophectoderm (TE). Here, we aim...
18.
Ward C, Volpe G, Cauchy P, Ptasinska A, Almaghrabi R, Blakemore D, et al.
Cell Rep
. 2018 Aug;
24(6):1496-1511.e8.
PMID: 30089261
During somatic reprogramming, Yamanaka's pioneer factors regulate a complex sequence of molecular events leading to the activation of a network of pluripotency factors, ultimately resulting in the acquisition and maintenance...
19.
Yehuda Y, Blumenfeld B, Mayorek N, Makedonski K, Vardi O, Cohen-Daniel L, et al.
Nucleic Acids Res
. 2018 Jul;
46(16):8299-8310.
PMID: 29986092
Mammalian DNA replication is a highly organized and regulated process. Large, Mb-sized regions are replicated at defined times along S-phase. Replication Timing (RT) is thought to play a role in...
20.
Masika H, Farago M, Hecht M, Condiotti R, Makedonski K, Buganim Y, et al.
Nat Struct Mol Biol
. 2017 Nov;
24(12):1132-1138.
PMID: 29131141
Many regions of the genome replicate asynchronously and are expressed monoallelically. It is thought that asynchronous replication may be involved in choosing one allele over the other, but little is...