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Yoonji Baek

Explore the profile of Yoonji Baek including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 420
Followers 0
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Recent Articles
1.
Yin X, Cui Y, Kim R, Stiles W, Park S, Wang H, et al.
Theranostics . 2022 Jun; 12(9):4147-4162. PMID: 35673583
Enormous efforts have been made to integrate various therapeutic interventions into multifunctional nanoplatforms, resulting in the advance of nanomedicine. Image-guided drug delivery plays a pivotal role in this field by...
2.
Yokomizo S, Henary M, Buabeng E, Fukuda T, Monaco H, Baek Y, et al.
Adv Sci (Weinh) . 2022 May; 9(20):e2201416. PMID: 35567348
Fluorescence-guided surgery (FGS) aids surgeons with real-time visualization of small cancer foci and borders, which improves surgical and prognostic efficacy of cancer. Despite the steady advances in imaging devices, there...
3.
Park S, Kim R, Stiles W, Jo M, Zeng L, Rho S, et al.
Adv Sci (Weinh) . 2022 Mar; 9(15):e2200872. PMID: 35343104
Deferoxamine (DFO) is an FDA-approved iron-chelating agent which shows good therapeutic efficacy, however, its short blood half-life presents challenges such as the need for repeated injections or continuous infusions. Considering...
4.
Yadav Y, Owens E, Nomura S, Fukuda T, Baek Y, Kashiwagi S, et al.
J Med Chem . 2020 Aug; 63(17):9436-9445. PMID: 32787096
Highly stable symmetric and asymmetric squaraine fluorophores have been synthesized featuring an internal salt bridge between a quaternary ammonium cation and the central oxycyclobutenolate ring of the chromophore. Some of...
5.
Ji Y, Jones C, Baek Y, Park G, Kashiwagi S, Choi H
Adv Drug Deliv Rev . 2020 Jun; 167:121-134. PMID: 32579891
Near-infrared (NIR) light possesses many suitable optophysical properties for medical imaging including low autofluorescence, deep tissue penetration, and minimal light scattering, which together allow for high-resolution imaging of biological tissue....
6.
Hwang D, Jo M, Lee J, Kang H, Bao K, Hu S, et al.
Adv Ther (Weinh) . 2020 Apr; 2(11). PMID: 32318623
The physicochemical properties of nanomaterials play a key role in tissue-specific targeting by reducing nonspecific background uptake as well as controlling biodistribution and clearance. Due to the strong influence of...
7.
Usama S, Park G, Nomura S, Baek Y, Choi H, Burgess K
Bioconjug Chem . 2020 Jan; 31(2):248-259. PMID: 31909595
Some heptamethine cyanine dyes accumulate in solid tumors and persist there for several days. The reasons why they accumulate and persist in tumors were incompletely defined, but explanations based on...
8.
Kang H, Stiles W, Baek Y, Nomura S, Bao K, Hu S, et al.
Adv Mater . 2019 Dec; 32(6):e1905899. PMID: 31854033
Advances in molecular imaging modalities have accelerated the diagnosis and treatment of human diseases. However, tumors less than 1 cm in size still remain difficult to localize by conventional means...
9.
Kang H, Rho S, Stiles W, Hu S, Baek Y, Hwang D, et al.
Adv Healthc Mater . 2019 Dec; 9(1):e1901223. PMID: 31794153
Passive targeting of large nanoparticles by the enhanced permeability and retention (EPR) effect is a crucial concept for solid tumor targeting in cancer nanomedicine. There is, however, a trade-off between...
10.
Kang H, Han M, Xue J, Baek Y, Chang J, Hu S, et al.
Nat Commun . 2019 Nov; 10(1):5134. PMID: 31723130
Iron chelators have been widely used to remove excess toxic iron from patients with secondary iron overload. However, small molecule-based iron chelators can cause adverse side effects such as infection,...