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Yongxu Jia

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Articles 27
Citations 424
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Recent Articles
1.
Wang Z, Chen C, Ai J, Gao Y, Wang L, Xia S, et al.
MedComm (2020) . 2025 Jan; 6(1):e70048. PMID: 39811803
Cellular senescence is characterized by a stable cell cycle arrest and a hypersecretory, proinflammatory phenotype in response to various stress stimuli. Traditionally, this state has been viewed as a tumor-suppressing...
2.
Sui X, Wang W, Zhang D, Xu J, Li J, Jia Y, et al.
Gene . 2024 Jun; 927:148701. PMID: 38885819
Background: Cancer stem cells (CSCs) play a significant role in the recurrence and drug resistance of esophageal carcinoma (ESCA). Ferroptosis is a promising anticancer therapeutic strategy that effectively targets CSCs...
3.
Wang L, Ge J, Han H, Jia Y, Qin Y
Cancer Lett . 2024 May; 594:216986. PMID: 38797233
Recent advancements in understanding the tumor microenvironment (TME) have highlighted the critical role of the nervous system in cancer progression. This review comprehensively examines how the nervous system influences various...
4.
Chang Z, Jia Y, Gao M, Song L, Zhang W, Zhao R, et al.
Biol Direct . 2024 Mar; 19(1):19. PMID: 38429756
Background: Esophageal squamous cell carcinoma (ESCC) is the main subtype of esophageal cancer. Current therapeutic effect is far from satisfaction. Hence, identifying susceptible genes and potential targets is necessary for...
5.
Wang Z, Chen C, Shu J, Ai J, Liu Y, Cao H, et al.
Cancer Cell Int . 2024 Jan; 24(1):44. PMID: 38273348
Background: Gastric cancer (GC) ranks fifth for morbidity and third for mortality worldwide. The N-methyladenosine (mA) mRNA methylation is crucial in cancer biology and progression. However, the relationship between mA...
6.
Ding Y, Wang Z, Chen C, Li D, Wang W, Jia Y, et al.
Carcinogenesis . 2023 Nov; 45(1-2):45-56. PMID: 37971062
Objective: Gastric cancer (GC) is prevalent worldwide but has a dismal prognosis, and its molecular and pathogenic pathways remain unknown. Kallikrein 11 (KLK11) has a reduced expression in GC and...
7.
Wang Z, Chen C, Ai J, Shu J, Ding Y, Wang W, et al.
Comput Biol Med . 2023 Jul; 163:107227. PMID: 37413850
Gastric carcinoma (GC) is the fourth leading cause of cancer-related mortality worldwide. Patients with advanced GC tend to have poor prognoses and shortened survival. Finding novel predictive biomarkers for GC...
8.
Jia Y, Zhang B, Zhang C, Kwong D, Chang Z, Li S, et al.
Adv Sci (Weinh) . 2023 Jan; 10(7):e2204565. PMID: 36709495
Lymph node metastasis, the leading cause of mortality in esophageal squamous carcinoma (ESCC) with a highly complex tumor microenvironment, remains underexplored. Here, the transcriptomes of 85 263 single cells are...
9.
Wang Z, Chen C, Wang L, Jia Y, Qin Y
Front Immunol . 2023 Jan; 13:1050522. PMID: 36618390
Multiple myeloma (MM) is a malignant plasma cell disorder that remains incurable for most patients, as persistent clonal evolution drives new mutations which confer MM high-risk signatures and resistance to...
10.
Jia Y, Yan Q, Zheng Y, Li L, Zhang B, Chang Z, et al.
J Exp Clin Cancer Res . 2022 Sep; 41(1):287. PMID: 36171622
Background: Lymph node metastasis is one of most common determinants of the stage and prognosis of gastric cancer (GC). However, the key molecular events and mechanisms mediating lymph node metastasis...