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Yongxin Zhu

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Articles 28
Citations 211
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Recent Articles
11.
Du P, Zheng J, Wang S, Lou Y, Zhang Z, Wang J, et al.
Int J Mol Sci . 2023 Apr; 24(8). PMID: 37108179
Immunosuppression plays a significant role in tumor recurrence and metastasis, ultimately causing poor survival outcomes. Overcoming immunosuppression and stimulating durable antitumor immunity are essential for tumor treatment. In our previous...
12.
Chen L, Wang F, Qu S, He X, Zhu Y, Zhou Y, et al.
Antioxidants (Basel) . 2022 Feb; 11(2). PMID: 35204061
Vulvovaginal candidiasis (VVC) is one of the most frequent diseases induced by () during pregnancy, which results in enormous pain to women and their partners in daily life. Perillaldehyde (PAE),...
13.
Huang Z, Huang J, Tian L, Wang N, Zhu Y, Wang H, et al.
Sensors (Basel) . 2021 Jan; 21(3). PMID: 33499338
A three-dimensional (3D) image sensor based on Single-Photon Avalanche Diode (SPAD) requires a time-to-digital converter (TDC) with a wide dynamic range and fine resolution for precise depth calculation. In this...
14.
Song Y, Zhu Y, Nan T, Hou J, Du S, Song S
Sensors (Basel) . 2020 Jul; 20(15). PMID: 32707801
The SKA (Square Kilometer Array) radio telescope will become the most sensitive telescope by correlating a huge number of antenna nodes to form a vast array of sensors in a...
15.
Zhu Y, Zalaznick J, Sleczka B, Parrish K, Yang Z, Olah T, et al.
Rapid Commun Mass Spectrom . 2020 Jul; 34(20):e8896. PMID: 32666620
Rationale: High tumor expression of programmed cell death protein (PD1) and programmed death-ligand 1 (PD-L1) is thought to be associated with positive clinical outcomes after treatment with anti-PD1 or anti-PD-L1...
16.
Lu G, Tian P, Zhu Y, Zuo X, Li X
J Biosci . 2020 Apr; 45. PMID: 32345778
Oxidative low-density lipoprotein (ox-LDL)-induced endothelial cell injury is a key contributor to atherosclerosis development. However, the role and mechanism of long noncoding RNA X-inactive specific transcript (XIST) in atherosclerosis remain...
17.
Ciccimaro E, Zhu Y, Ostanin D, Suchard S, MacGuire J, Xiao Q, et al.
Anal Chem . 2017 Apr; 89(9):5115-5123. PMID: 28383906
We demonstrate a novel strategy using affinity extraction (AE) LC-MS to directly measure drug exposure and target engagement, two critical pharmacological questions, with a single assay. The assay measures total...
18.
Li W, Trouba K, Ma L, Kwagh J, Storck C, Zhu Y, et al.
Int J Toxicol . 2017 Jan; 36(1):35-49. PMID: 28056568
BMS-986094, a 2'-C-methylguanosine prodrug for the treatment of chronic hepatitis C virus infection, was withdrawn from phase 2 clinical trials because of unexpected cardiac and renal toxicities. To better understand...
19.
Huang A, Jayaraman L, Fura A, Vite G, Trainor G, Gottardis M, et al.
ACS Med Chem Lett . 2016 Jan; 7(1):40-5. PMID: 26819663
Efforts to identify a potent, reversible, nonsteroidal CYP17A1 lyase inhibitor with good selectivity over CYP17A1 hydroxylase and CYPs 11B1 and 21A2 for the treatment of castration-resistant prostate cancer (CRPC) culminated...
20.
Zhu Y, DArienzo C, Lou Z, Kozhich A, Madireddi M, Chimalakonda A, et al.
Bioanalysis . 2016 Jan; 8(3):193-204. PMID: 26811930
Background: Therapeutic protein discovery study highlights the need for the development of quantitative bioanalytical methods for determining the levels of both the therapeutic protein and the target protein, as well....