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Yongqi Zhen

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Articles 18
Citations 206
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Recent Articles
1.
Lu Y, Zhen Y, Li Z, Luo B, Yin B, Zhang L
Int J Biol Macromol . 2025 Feb; 306(Pt 1):141303. PMID: 39999718
No abstract available.
2.
Lu Y, Zhen Y, Li Z, Luo B, Yin B, Zhang L
Int J Biol Macromol . 2024 Dec; 286:138398. PMID: 39647747
Sequence similarity 20 family member C (Fam20C), a Golgi casein kinase, has a gradually elucidated mechanism in triple-negative breast cancer (TNBC) and is considered a possible target for therapeutic intervention....
3.
Li Z, Lu Y, Zhen Y, Jin W, Ma X, Yuan Z, et al.
Phytomedicine . 2024 Nov; 135:156209. PMID: 39515096
Background: Alzheimer's disease (AD) is a widespread neurodegenerative disorder for which effective therapies remain elusive, primarily due to the complexity of its underlying pathophysiology. In recent years, natural products have...
4.
Zhou Y, Liao M, Li Z, Ye J, Wu L, Mou Y, et al.
Int J Mol Sci . 2023 Oct; 24(20). PMID: 37894802
Paclitaxel, a natural anticancer drug, is widely recognized and extensively utilized in the treatment of breast cancer (BC). However, it may lead to certain side effects or drug resistance. Fortunately,...
5.
Huang Y, Zhen Y, Chen Y, Sui S, Zhang L
Biochem Pharmacol . 2023 Oct; 217:115842. PMID: 37802240
RAS/RAF/MEK/ERK signaling pathway is one of the most important pathways of Mitogen-activated protein kinases (MAPK), which widely participate in regulating cell proliferation, differentiation, apoptosis and signaling transduction. Autophagy is an...
6.
Zhang L, Zhen Y, Feng L, Li Z, Lu Y, Wang G, et al.
Eur J Med Chem . 2023 Jul; 259:115648. PMID: 37478560
Triple negative breast cancer (TNBC) is one of the most aggressive breast tumors, with a high rate of recurrence and metastasis as well as a poor prognosis. Consequently, it is...
7.
Bu H, Li Z, Lu Y, Zhuang Z, Zhen Y, Zhang L
Eur J Med Chem . 2023 Apr; 255:115404. PMID: 37098296
Dual leucine zipper kinase (DLK, MAP3K12), a serine/threonine protein kinase, plays a key role in neuronal development, as it regulates axon regeneration and degeneration through its downstream kinase. Importantly, DLK...
8.
Zou L, Liao M, Zhen Y, Zhu S, Chen X, Zhang J, et al.
Acta Pharm Sin B . 2022 Oct; 12(10):3743-3782. PMID: 36213540
UNC-51-like kinase 1 (ULK1), as a serine/threonine kinase, is an autophagic initiator in mammals and a homologous protein of autophagy related protein (Atg) 1 in yeast and of UNC-51 in...
9.
Zhou Y, Zhen Y, Wang G, Liu B
Front Neuroanat . 2022 Jun; 16:910427. PMID: 35756499
Neurodegenerative diseases (NDs) are becoming a serious public health concern as the world's population continues to age, demanding the discovery of more effective therapies. Excessive formation of reactive oxygen species...
10.
Zhen Y, Yuan Z, Zhang J, Chen Y, Fu Y, Liu Y, et al.
Cell Death Dis . 2022 Apr; 13(4):375. PMID: 35440104
Breast cancer is still one of the most common malignancies worldwide and remains a major clinical challenge. We previously reported that the anthelmintic drug flubendazole induced autophagy and apoptosis via...