Yonglong Chen
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Explore the profile of Yonglong Chen including associated specialties, affiliations and a list of published articles.
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65
Citations
1261
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Recent Articles
21.
Fan S, Chen Y, Jiang Y, Hu K, Li C
Biochem Biophys Res Commun
. 2020 Sep;
533(3):613-619.
PMID: 32981679
c-Myc modulator 1 (MM1), also known as PFDN5, is the fifth subunit of prefoldin. It was previously reported that MM1-based prefoldin promotes folding of actin during assembly of cytoskeleton, which...
22.
Hu Z, Wang L, Shi Z, Jiang J, Li X, Chen Y, et al.
Cell Biosci
. 2019 Nov;
9:87.
PMID: 31673328
Overlap extension polymerase chain reaction (PCR) is a powerful technology for DNA assembly. Based on this technology, we synthesized DNA templates, which were transcribed into sgRNA in vitro, and further...
23.
Shi Z, Xin H, Tian D, Lian J, Wang J, Liu G, et al.
FASEB J
. 2019 Mar;
33(6):6962-6968.
PMID: 30844313
Precise single-base editing in would greatly expand the utility of this true diploid frog for modeling human genetic diseases caused by point mutations. Here, we report the efficient conversion of...
24.
Li T, Deng Y, Shi Y, Tian R, Chen Y, Zou L, et al.
Oncogene
. 2018 Jul;
37(47):6180-6194.
PMID: 30013190
Aberrant activation of anaplastic lymphoma kinase (ALK) can cause sporadic and familial neuroblastoma. Using a proteomics approach, we identified Bruton's tyrosine kinase (BTK) as a novel ALK interaction partner, and...
25.
Chen Y, Li Y, Peng Y, Zheng X, Fan S, Yi Y, et al.
Cell Death Differ
. 2018 Jun;
25(12):2118-2129.
PMID: 29880857
p63 and c-Myc are key transcription factors controlling genes involved in the cell cycle and cellular senescence. We previously reported that p63α can destabilize MM1 protein to derepress c-Myc, resulting...
26.
He H, Peng Y, Fan S, Chen Y, Zheng X, Li C
FEBS Lett
. 2018 May;
592(13):2334-2340.
PMID: 29782646
Potassium channel tetramerization domain containing 5 (KCTD5) was previously documented as a component of the Cullin3-RING ligase (CRL3). It has been reported that KCTD5 can induce enrichment of polyubiquitinated proteins,...
27.
Hu Z, Shi Z, Guo X, Jiang B, Wang G, Luo D, et al.
Cell Biosci
. 2018 Feb;
8:12.
PMID: 29468011
Background: Precise genome editing is essential for both basic and translational research. The recently developed CRISPR/Cas9 system can specifically cleave a designated site of target gene to create a DNA...
28.
Sun J, Wang X, Shi Y, Li J, Li C, Shi Z, et al.
Biochem Biophys Res Commun
. 2017 Dec;
495(2):1580-1587.
PMID: 29223398
Eph/ephrin molecules are widely expressed during embryonic development, and function in a variety of developmental processes. Here we studied the roles of the Eph receptor EphA7 and its soluble form...
29.
Chen Y, Peng Y, Fan S, Li Y, Xiao Z, Li C
Cell Mol Life Sci
. 2017 Oct;
75(6):965-973.
PMID: 28975366
As a member of tumor suppressor p53 family, p63, a gene encoding versatile protein variant, has been documented to correlate with cancer formation and progression, though it is rarely mutated...
30.
Zhang Z, Lei A, Xu L, Chen L, Chen Y, Zhang X, et al.
J Biol Chem
. 2017 Jun;
292(31):12842-12859.
PMID: 28634230
Cancer cells are immature cells resulting from cellular reprogramming by gene misregulation, and redifferentiation is expected to reduce malignancy. It is unclear, however, whether cancer cells can undergo terminal differentiation....