Yongke Lu
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Explore the profile of Yongke Lu including associated specialties, affiliations and a list of published articles.
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62
Citations
1886
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Recent Articles
1.
George J, Lu Y, Tsuchishima M, Tsutsumi M
Redox Biol
. 2024 Jul;
75:103258.
PMID: 38970988
Ischemia-reperfusion (IR) or reoxygenation injury is the paradoxical exacerbation of cellular impairment following restoration of blood flow after a period of ischemia during surgical procedures or other conditions. Acute interruption...
2.
Chen X, Wang L, Denning K, Mazur A, Xu Y, Wang K, et al.
Biomedicines
. 2024 May;
12(5).
PMID: 38790950
Obesity results in hepatic fat accumulation, i.e., steatosis. In addition to fat overload, impaired fatty acid β-oxidation also promotes steatosis. Fatty acid β-oxidation takes place in the mitochondria and peroxisomes....
3.
Lu Y, George J
Am J Physiol Gastrointest Liver Physiol
. 2024 Apr;
326(5):G483-G494.
PMID: 38573193
Fatty acid oxidation (FAO) releases the energy stored in fat to maintain basic biological processes. Dehydrogenation is a major way to oxidize fatty acids, which needs NAD to accept the...
4.
Xu C, Acevedo P, Lu Y, Su B, Ozuna K, Padilla V, et al.
Int J Geriatr Psychiatry
. 2023 Dec;
38(12):e6037.
PMID: 38100638
Objectives: The trail making test part B (TMT-B) evaluates executive functions, memory, and sensorimotor functions. No previous study was found to examine the longitudinal effect of APOE-ε4 genotypes on the...
5.
Wang K, Theeke L, Liao C, Wang N, Lu Y, Xiao D, et al.
J Neurol Sci
. 2023 Sep;
453:120812.
PMID: 37776718
Objective: Metabolic biomarkers can potentially inform disease progression in Alzheimer's disease (AD). The purpose of this study is to identify and describe a new set of diagnostic biomarkers for developing...
6.
Chen X, Denning K, Mazur A, Lawrence L, Wang X, Lu Y
Free Radic Biol Med
. 2023 Aug;
208:221-228.
PMID: 37567517
In peroxisomes, acyl-CoA oxidase (ACOX) oxidizes fatty acids and produces HO, and the latter is decomposed by catalase. If ethanol is present, ethanol will be oxidized by catalase coupling with...
7.
Zhang P, Lu Y, Li Y, Wang K, An H, Tan Y
Genes Genomics
. 2023 Jul;
45(10):1317-1328.
PMID: 37414911
Background: Tardive dyskinesia (TD) develops in 20-30% of schizophrenia patients and up to 50% in patients > 50 years old. DNA methylation may play an important role in the development...
8.
Xu Y, Lu Y
Biochem Biophys Res Commun
. 2022 Jun;
619:84-89.
PMID: 35749940
Fibroblast growth factor 21 (FGF21) is regulated by peroxisome proliferator activated receptor α (PPARα) in the liver. FGF21 regulates lipid metabolism via fibroblast growth factor receptor 1 (FGFR1). FGF21 protect...
9.
Xu Y, Denning K, Lu Y
Biochem Biophys Res Commun
. 2022 May;
613:47-52.
PMID: 35526488
Peroxisome proliferator-activated receptor α (PPARα) regulates fatty acid oxidation (FAO). Usually, very-long chain fatty acids are first activated by acyl-CoA synthetase (ACS) to generate acyl-CoA for oxidation by acyl-CoA oxidase...
10.
Wang K, Lu Y, Morrow D, Xiao D, Xu C
J Mol Neurosci
. 2022 Feb;
72(5):1085-1097.
PMID: 35171450
The Rho GTPase activating protein 26 (ARHGAP26) gene has been reported to be associated with neuropsychiatric diseases and neurodegenerative diseases including Parkinson's disease. We examined whether the ARHGAP26 gene is...