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Yongfang Yao

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Articles 109
Citations 696
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Recent Articles
1.
Wei Z, Han B, Yang L, Zhao J, Nakai T, Chen S, et al.
Eur J Med Chem . 2025 Mar; 289:117451. PMID: 40037063
P2YR is activated by UDP (uridine diphosphate) and UDP glucose and associated with the development of many inflammatory diseases. P2YR antagonists are expected to be a new choice for the...
2.
Mao S, Liu W, Wang X, Wang M, Wang S, Yao Y, et al.
J Med Chem . 2025 Jan; 68(3):2483-2503. PMID: 39878051
The P2YR is activated by UDP and UDP glucose and is involved in many human inflammatory diseases. Based on the molecular docking analysis of currently reported P2YR antagonists and the...
3.
Yao Y, Qiu S, Xue Y, Wang B, Zhang Y, Wang X
J Clin Nurs . 2024 Dec; 34(2):332-344. PMID: 39627944
Background: Virtual reality is an emerging non-drug treatment for pain caused by endoscopy procedure. We conducted a meta-analysis to evaluate the effectiveness and safety of virtual reality based interventions for...
4.
Zhao Y, Han B, Wei Z, Li Y, Yao Y, Song C, et al.
Eur J Med Chem . 2024 Sep; 279:116890. PMID: 39341096
The P2Y receptor (P2YR), as a crucial member of the purine family, is a potential therapeutic target for the treatment of intestinal inflammation, tracheal inflammation and diabetes. We first discovered...
5.
Li Z, Han B, Qi M, Li Y, Duan Y, Yao Y
Biochim Biophys Acta Rev Cancer . 2024 Aug; 1879(5):189172. PMID: 39151808
Macrophage-mediated programmed cell removal (PrCR) is crucial for the identification and elimination of needless cells that maintain tissue homeostasis. The efficacy of PrCR depends on the balance between pro-phagocytic "eat...
6.
Liu Z, Mao S, Li H, Liu W, Tao J, Lu Y, et al.
Bioorg Chem . 2024 Aug; 151:107679. PMID: 39094510
Dual-target agents have more advantages than drug combinations for cancer treatment. Here, we designed and synthesized a series of novel VEGFR-2/tubulin dual-target inhibitors through a molecular hybridization strategy, and the...
7.
Xiong Y, Rozzi R, Zhang Y, Fan L, Zhao J, Li D, et al.
Sci Adv . 2024 Jul; 10(28):eadm8240. PMID: 38996028
Island vertebrates have evolved a number of morphological, physiological, and life history characteristics that set them apart from their mainland relatives. However, to date, the evolution of metabolism and its...
8.
Liu W, Mao S, Wang Y, Wang M, Li M, Sun M, et al.
J Med Chem . 2024 Jun; 67(12):10233-10247. PMID: 38874515
P2Y receptor (P2YR) is activated by uridine 5'-diphosphate-glucose, which is involved in many human inflammatory diseases. Based on the molecular docking analysis of currently reported P2YR antagonists and the crystallographic...
9.
Yu M, Yao Y, Li X, Su A, Xie M, Xiong Y, et al.
Int J Parasitol . 2024 Apr; 54(8-9):441-451. PMID: 38604548
Wild rhesus macaques are a potential source of zoonotic parasites for humans, and Entamoeba spp. are common intestinal parasites. To investigate the prevalence of Entamoeba in wild rhesus macaques in...
10.
Liu Z, Liu W, Han M, Wang M, Li Y, Yao Y, et al.
Phytomedicine . 2024 Mar; 128:155334. PMID: 38554573
Background: The P2X7 receptor (P2X7R) is known to play a significant role in regulating various pathological processes associated with immune regulation, neuroprotection, and inflammatory responses. It has emerged as a...