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Yongchang Wei

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Articles 91
Citations 1065
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Recent Articles
1.
Chen C, Cai Y, Hu W, Tan K, Lu Z, Zhu X, et al.
Cancer Discov . 2025 Mar; PMID: 40029140
Colorectal cancer (CRC) is a heterogeneous disease that develops through a stepwise accumulation, yet the underlying mechanisms at single-cell resolution remain unclear. Here, we profiled 751,531 single-cell transcriptomes, spatial transcriptomics,...
2.
Cai L, Yang Q, Shao X, Wang S, Fu Y, Mao X, et al.
Int J Biol Macromol . 2025 Feb; :141370. PMID: 39988177
The development of multifunctional therapies with targeted release materials is desirable for overcoming the high aggressiveness and poor prognosis of triple-negative breast cancer (TNBC). Herein, we have designed a self-assembled...
3.
Jin S, Qian W, Suo R, Li Y, Huan Ling , Li S, et al.
Anal Methods . 2025 Feb; 17(8):1892-1899. PMID: 39925080
Hydroxyl radicals (˙OH), highly reactive oxygen species involved in oxidative stress and cancer therapy, are challenging to detect intracellularly due to their short lifetime, low concentration, and high reactivity. To...
4.
Li B, Wu M, Geng H, Li Y, Chen Z, Lu Z, et al.
Carcinogenesis . 2024 Dec; 46(1. PMID: 39680067
Although genome-wide association studies have identified dozens of loci associated with colorectal cancer (CRC) susceptibility, the causal genes or risk variants within these loci and their biological functions often remain...
5.
Qian W, Zhang C, He L, Jin S, Suo R, Li Y, et al.
Bioorg Chem . 2024 Dec; 154:108021. PMID: 39642753
The potential of iron-based therapeutic agents in enhancing radiotherapy efficacy through catalyzing the Fenton reaction has garnered widespread interest. The inherent instability of ferrous ions requires the use of complex...
6.
Tian S, Liu Y, Liu P, Nomura S, Wei Y, Huang T
Int J Mol Sci . 2024 Oct; 25(19). PMID: 39409106
Depressive disorder contributes to the initiation and prognosis of patients with cancer, but the interaction between cancer and depressive disorder remains unclear. We generated a gastric adenocarcinoma patient-derived xenograft mice...
7.
Ning C, Jin M, Cai Y, Fan L, Hu K, Lu Z, et al.
BMC Med . 2024 Oct; 22(1):456. PMID: 39394562
Background: The hippocampus, with its complex subfields, is linked to numerous neuropsychiatric traits. While most research has focused on its global structure or a few specific subfields, a comprehensive analysis...
8.
Ning B, Huang T, Liu Y, Wei Y
Heliyon . 2024 Aug; 10(15):e34399. PMID: 39144985
Background: Depression and long non-coding RNA (lncRNA) have been reported to be associated with tumor progression and prognosis in gastric cancer (GC). This study aims to build a GC risk...
9.
Cui X, Hu Z, Li R, Jiang P, Wei Y, Chen Z
J Pharm Anal . 2024 Jul; 14(6):100969. PMID: 39027913
Hypoxia is the common characteristic of almost all solid tumors, which prevents therapeutic drugs from reaching the tumors. Therefore, the development of new targeted agents for the accurate diagnosis of...
10.
Deng X, Xu X, Xia S, Wang Z, Li Y, Huang T, et al.
Colloids Surf B Biointerfaces . 2024 Jul; 241:114060. PMID: 38964275
The conventional silver nanoparticles (Ag NPs) are characterized with high loading rate and stacking phenomenon, leading to shedding caused biotoxicity and low catalytic efficiency. This seriously hinders their application in...