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Yong-Hyun Ko

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Articles 28
Citations 188
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Recent Articles
1.
Seo J, Kim J, Ko Y, Lee B, Hur K, Jung Y, et al.
Biomol Ther (Seoul) . 2025 Feb; 33(2):268-277. PMID: 39933949
Although histone deacetylase 6 (HDAC6) is considered a therapeutic target for Alzheimer's disease (AD), its role in cholinergic dysfunction in AD patients remains unclear. This study investigated the effects of...
2.
Kim Y, Kim K, Lee Y, Min H, Ko Y, Lee B, et al.
Br J Pharmacol . 2024 May; 181(18):3327-3345. PMID: 38751203
Background And Purpose: Cytoplasmic fragile X messenger ribonucleoprotein 1 (FMR1)-interacting protein 2 (CYFIP2), as a component of the Wiskott-Aldrich syndrome protein family verprolin-homologous protein (WAVE) regulatory complex, is involved in...
3.
Kim Y, Kook W, Ma S, Lee B, Ko Y, Kim S, et al.
Arch Pharm Res . 2024 Mar; 47(4):360-376. PMID: 38551761
Novel psychoactive substances (NPSs) are new psychotropic drugs designed to evade substance regulatory policies. 25E-NBOMe (2-(4-ethyl-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine) has recently been identified as an NPS, and its recreational misuse has been reported...
4.
Lee B, Sung S, Hur K, Kim S, Ma S, Kim S, et al.
J Ginseng Res . 2022 Jan; 46(1):147-155. PMID: 35058731
Background: Methamphetamine (METH) is the most widely used psychostimulant and has been known to exhibit reinforcing effects even after long abstinence. We showed the inhibitory effect of Korean Red Ginseng...
5.
Hur K, Kim S, Ma S, Lee B, Ko Y, Seo J, et al.
Br J Pharmacol . 2021 May; 178(19):3869-3887. PMID: 33987827
Background And Purpose: Methoxphenidine is a dissociative-based novel psychoactive designer drug. Although fatal accidents from methoxphenidine abuse have been reported, recreational use of the drug continues. We aim to provide...
6.
Hur K, Ma S, Lee B, Ko Y, Seo J, Ryu H, et al.
Biomol Ther (Seoul) . 2021 May; 29(4):384-391. PMID: 33935046
Currently, the expanding recreational use of synthetic cannabinoids (SCBs) threatens public health. SCBs produce psychoactive effects similar to those of tetrahydrocannabinol, the main component of cannabis, and additionally induce unexpected...
7.
Lee B, Lee J, Ko Y, Seo J, Hur K, Kim Y, et al.
J Ginseng Res . 2021 Apr; 45(2):254-263. PMID: 33841006
Background: A chronic social defeat stress (CSDS) model has been proposed as relevant to stress-induced behavioral change in humans. In this study, we examined the effect of Korean Red Ginseng...
8.
Kim Y, Ma S, Hur K, Lee Y, Ko Y, Lee B, et al.
Arch Toxicol . 2021 Feb; 95(4):1431. PMID: 33608740
No abstract available.
9.
Kim Y, Ma S, Hur K, Lee Y, Ko Y, Lee B, et al.
Arch Toxicol . 2021 Jan; 95(4):1413-1429. PMID: 33515270
2C (2C-x) is the general name for the family of phenethylamines containing two methoxy groups at the 2 and 5 positions of the benzene ring. The abuse of 2C family...
10.
Ko Y, Kim S, Lee S, Jang C
Arch Pharm Res . 2020 Nov; 43(11):1128-1143. PMID: 33225387
Emotional disorders such as anxiety and depression are widespread psychological diseases that affect up to 20% of the world's population. There are many approaches to the discovery of novel agents...