Yone Phar Lin
Overview
Explore the profile of Yone Phar Lin including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
81
Followers
0
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Recent Articles
1.
Menon S, Breese M, Lin Y, Allegakoen H, Perati S, Heslin A, et al.
Res Sq
. 2023 Jul;
PMID: 37398210
The genetic principle of synthetic lethality is clinically validated in cancers with loss of specific DNA damage response (DDR) pathway genes (i.e. BRCA1/2 tumor suppressor mutations). The broader question of...
2.
Menon S, Gracilla D, Breese M, Lin Y, Cruz F, Feinberg T, et al.
bioRxiv
. 2023 May;
PMID: 37205599
While oncogenes promote cancer cell growth, unrestrained proliferation represents a significant stressor to cellular homeostasis networks such as the DNA damage response (DDR). To enable oncogene tolerance, many cancers disable...
3.
Tulpule A, Guan J, Neel D, Allegakoen H, Lin Y, Brown D, et al.
Cell
. 2021 Apr;
184(10):2649-2664.e18.
PMID: 33848463
Receptor tyrosine kinase (RTK)-mediated activation of downstream effector pathways such as the RAS GTPase/MAP kinase (MAPK) signaling cascade is thought to occur exclusively from lipid membrane compartments in mammalian cells....