Yoav Altman
Overview
Explore the profile of Yoav Altman including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
427
Followers
0
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Recent Articles
1.
Miller K, Li B, Pierce-Hoffman H, Patel S, Lei X, Rajesh A, et al.
Nat Commun
. 2025 Mar;
16(1):2229.
PMID: 40044657
Genomic instability and inflammation are distinct hallmarks of aging, but the connection between them is poorly understood. Here we report a mechanism directly linking genomic instability and inflammation in senescent...
2.
Miller K, Li B, Pierce-Hoffman H, Patel S, Lei X, Rajesh A, et al.
bioRxiv
. 2023 Dec;
PMID: 38045344
Genomic instability and inflammation are distinct hallmarks of aging, but the connection between them is poorly understood. Understanding their interrelationship will help unravel new mechanisms and therapeutic targets of aging...
3.
Hsieh L, Sidney J, Burns J, Boyle D, Firestein G, Altman Y, et al.
J Immunol
. 2021 Feb;
206(6):1194-1203.
PMID: 33579724
We described a human regulatory T cell (Treg) population activated by IgG B cells presenting peptides of the heavy C region (Fc) via processing of the surface IgG underlying a...
4.
Marki A, Buscher K, Lorenzini C, Meyer M, Saigusa R, Fan Z, et al.
J Exp Med
. 2020 Dec;
218(3).
PMID: 33275138
Rolling neutrophils form tethers with submicron diameters. Here, we report that these tethers detach, forming elongated neutrophil-derived structures (ENDS) in the vessel lumen. We studied ENDS formation in mice and...
5.
Kasperkiewicz P, Altman Y, DAngelo M, Salvesen G, Drag M
J Am Chem Soc
. 2017 Jul;
139(29):10115-10125.
PMID: 28672107
Neutrophils, the front line defenders against infection, express four serine proteases (NSPs) that play roles in the control of cell-signaling pathways and defense against pathogens and whose imbalance leads to...
6.
Sharma G, Valenta D, Altman Y, Harvey S, Xie H, Mitragotri S, et al.
J Control Release
. 2010 Aug;
147(3):408-12.
PMID: 20691741
The interaction of macrophages with micro and nanoparticles (MNPs) is important because these cells clear particles from the circulation, and because they are potential therapeutic targets in inflammatory conditions, atherosclerosis...
7.
Tanaka Y, Bi K, Kitamura R, Hong S, Altman Y, Matsumoto A, et al.
Immunity
. 2003 Mar;
18(3):403-14.
PMID: 12648457
We describe the isolation of a protein, SWAP-70-like adapter of T cells (SLAT), which is expressed at high levels in thymocytes and differentiated Th2 cells. SLAT expression was upregulated in...
8.
Villalba M, Bi K, Hu J, Altman Y, Bushway P, Reits E, et al.
J Cell Biol
. 2002 Apr;
157(2):253-63.
PMID: 11956228
PKCtheta plays an essential role in activation of mature T cells via stimulation of AP-1 and NF-kappaB, and is known to selectively translocate to the immunological synapse in antigen-stimulated T...
9.
Fang D, Elly C, Gao B, Fang N, Altman Y, Joazeiro C, et al.
Nat Immunol
. 2002 Feb;
3(3):281-7.
PMID: 11828324
Itch is an E3 ubiquitin ligase that is disrupted in nonagouti-lethal or itchy mice. Itch deficiency leads to severe immune and inflammatory disorders and constant itching of the skin. Here...