Yinhua Lu
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Explore the profile of Yinhua Lu including associated specialties, affiliations and a list of published articles.
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59
Citations
893
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Recent Articles
1.
Lv L, Liu S, Fu Y, Zhang Y, Wang M, Sun J, et al.
Nucleic Acids Res
. 2024 Dec;
53(2.
PMID: 39704119
Programmable control of bacterial gene expression holds great significance for both applied and academic research. This is particularly true for Streptomyces, a genus of Gram-positive bacteria and major producers of...
2.
Qin W, Xu L, Cheng K, Lu Y, Yang Z
Appl Microbiol Biotechnol
. 2024 Sep;
108(1):474.
PMID: 39320489
(R)-3-Isobutylglutarate monoamide (R-IBM) is a key intermediate in the synthesis of the analgesic drug pregabalin. Recently, the imidase BpIH derived from Burkholderia phytofirmans was identified as a promising catalyst for...
3.
Wang S, Zeng X, Jiang Y, Wang W, Bai L, Lu Y, et al.
Nat Prod Rep
. 2024 Jun;
41(9):1441-1455.
PMID: 38888887
Covering: up to the end of 2023Type I CRISPR-Cas systems are widely distributed, found in over 40% of bacteria and 80% of archaea. Among genome-sequenced actinomycetes (particularly spp.), 45.54% possess...
4.
Li Z, He L, Wang X, Huo Q, Zheng G, Kong D, et al.
J Biol Chem
. 2023 Mar;
299(4):104573.
PMID: 36870685
Sideromycins are a unique subset of siderophores comprising of a siderophore conjugated to an antimicrobial agent. The "Trojan horse" antibiotic albomycins are unique sideromycins consisting of a ferrichrome-type siderophore conjugated...
5.
Yu Z, Chang Z, Lu Y, Xiao H
FEMS Yeast Res
. 2023 Mar;
23.
PMID: 36869777
Due to its wide availability, glycerol is considered as a promising alternative feedstock for microbial fermentation. As a model eukaryote, Saccharomyces cerevisiae is commonly adopted for bioproduction of various bulk...
6.
Jin S, Hui M, Lu Y, Zhao Y
World J Microbiol Biotechnol
. 2023 Jan;
39(3):78.
PMID: 36645528
The two-component system (TCS) found in various organisms is a regulatory system, which is involved in the response by the organism to stimuli, thereby regulating the internal behavior of the...
7.
Chang Z, Li Y, Lu Y, Xiao H
Enzyme Microb Technol
. 2022 Nov;
162:110148.
PMID: 36343469
Terpenoids and steroids are two large families of natural products with diverse biological activities. C3 oxidase and acetyltransferase are the key enzymes in the post-modification of terpenoids and steroids, while...
8.
He W, Wang W, Ma J, Zheng G, Zimin A, Jiang W, et al.
Appl Microbiol Biotechnol
. 2022 Feb;
106(5-6):2147-2159.
PMID: 35218390
Rapamycin is an important macrocyclic antibiotic produced by Streptomyces rapamycinicus. In the rapamycin biosynthetic gene cluster (BGC), there are up to five regulatory genes, which have been shown to play...
9.
Zhu Y, Zhang P, Lu T, Wang X, Li A, Lu Y, et al.
Environ Microbiol
. 2021 Aug;
23(11):6907-6923.
PMID: 34390613
Phosphate metabolism is known to be regulated by the PhoPR regulatory system in Streptomyces and some other bacteria. In this study, we report that MtrA also regulates phosphate metabolism in...
10.
Wang W, Zheng G, Lu Y
Front Bioeng Biotechnol
. 2021 Jul;
9:692797.
PMID: 34327194
Microbial natural products (NPs) are a major source of pharmacological agents. Most NPs are synthesized from specific biosynthetic gene clusters (BGCs). With the rapid increase of sequenced microbial genomes, large...