Yinghuai Zhu
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Explore the profile of Yinghuai Zhu including associated specialties, affiliations and a list of published articles.
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20
Citations
106
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Recent Articles
1.
Zhang Y, Coghi P, Ren Z, Hosmane N, Zhu Y
Med Res Rev
. 2024 Dec;
PMID: 39690514
Targeted charged alpha- and beta-particle therapies are currently being used in clinical radiation treatments as newly developed methods for either killing or controlling tumor cell growth. The alpha particles can...
2.
Zhang Y, Cai J, Hosmane N, Zhu Y
Eur J Med Chem
. 2024 Sep;
279:116841.
PMID: 39244862
Boron neutron capture therapy (BNCT) is a highly targeted, selective and effective technique to cure various types of cancers, with less harm to the healthy cells. In principle, BNCT treatment...
3.
Zhang X, Lin Y, Hosmane N, Zhu Y
Med Rev (2021)
. 2024 Jan;
3(5):425-443.
PMID: 38283251
Boron neutron capture therapy (BNCT) is a potential radiation therapy modality for cancer, and tumor-targeted stable boron-10 (B) delivery agents are an important component of BNCT. Currently, two low-molecular-weight boron-containing...
4.
Coghi P, Li J, Hosmane N, Zhu Y
Med Res Rev
. 2023 Apr;
43(5):1809-1830.
PMID: 37102375
Boron neutron capture therapy (BNCT) is one of the most promising treatments among neutron capture therapies due to its long-term clinical application and unequivocally obtained success during clinical trials. Boron...
5.
Zhu Y, Prommana P, Hosmane N, Coghi P, Uthaipibull C, Zhang Y
ACS Omega
. 2022 Feb;
7(7):5864-5869.
PMID: 35224347
Boron nanoparticles (BNPs), functionalized with hydroxyl groups, were synthesized by a cascade process, followed by bromination and hydrolyzation reactions. These functionalized BNPs, (B (OH) ), were characterized using H and...
6.
Zhu Y, Cai J, Hosmane N, Suzuki M, Uno K, Zhang Y, et al.
Chem Commun (Camb)
. 2021 Sep;
57(79):10174-10177.
PMID: 34528644
Carboxyboranylamino ethanol (MeN(BHCOH)CHCHOH, 1) was prepared in 75.0% yield by an amine-exchange reaction. Compound 1 shows lower cytotoxicity and higher anti-tumor efficacy towards the SCCVII cell line in comparison with...
7.
Coghi P, Zhu Y, Xie H, Hosmane N, Zhang Y
Molecules
. 2021 Jun;
26(11).
PMID: 34072937
The unique electron deficiency and coordination property of boron led to a wide range of applications in chemistry, energy research, materials science and the life sciences. The use of boron-containing...
8.
Cai J, Hosmane N, Takagaki M, Zhu Y
Molecules
. 2020 Oct;
25(20).
PMID: 33066470
In comparison with pristine sinomenine and carborane precursors, the calculations of molecular docking with matrix metalloproteinases (MMPs) and methylcarboranyl--butyl sinomenine showed improved interactions. Accordingly, methylcarboranyl--butyl sinomenine shows a high potential...
9.
Ali F, Hosmane N, Zhu Y
Molecules
. 2020 Feb;
25(4).
PMID: 32070043
Boron compounds now have many applications in a number of fields, including Medicinal Chemistry. Although the uses of boron compounds in pharmacological science have been recognized several decades ago, surprisingly...
10.
Zhu Y, Lin Y, Hosmane N
Bioorg Chem
. 2019 Jul;
90:103090.
PMID: 31260876
Reactions of closo-1-Me-2-Iodobutyl-1,2-closo-dicarborane, 1-Me-2-I(CH)-CBH, with l-dopa methyl ester can produce carboranyl l-dopa methyl esters in 54% yield in the presence of sodium hydroxide. The appended closo-carboranes can be decapitated with...