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Ying-Jhen Su

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Articles 9
Citations 279
Followers 0
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Recent Articles
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Su Y, Lin W, Chang Y, Wei K, Liang C, Chen S, et al.
Oncotarget . 2015 Oct; 6(35):38029-45. PMID: 26515729
CD133 is widely used as a surface marker to isolate cancer stem cells (CSCs). Here we show that in CSCs CD133 contributes to β-catenin-mediated transcriptional activation and to the self-renewal...
3.
Chang Y, Su Y, Hsiao M, Wei K, Lin W, Liang C, et al.
Cancer Res . 2015 Jul; 75(16):3398-410. PMID: 26122848
Wnt signaling contributes to the reprogramming and maintenance of cancer stem cell (CSC) states that are activated by epithelial-mesenchymal transition (EMT). However, the mechanistic relationship between EMT and the Wnt...
4.
Su Y, Lai H, Chang Y, Chen G, Lee J
EMBO J . 2011 Jun; 30(15):3186-99. PMID: 21701559
Cancer progression is commonly segregated into processes of primary tumour growth and secondary metastasis. Recent evidence suggests that a subpopulation of cancer cells, cancer stem cells (CSCs), is responsible for...
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Su Y, Tsai M, Kuo Y, Chiu Y, Cheng C, Lin S, et al.
Mol Pharmacol . 2010 Jan; 77(4):633-43. PMID: 20042515
Emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone derivative found in the roots and rhizomes of numerous plants. It is a tyrosine kinase inhibitor and has anticancer effects on lung cancer. Rad51...
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Ko J, Su Y, Lin S, Jhan J, Ciou S, Cheng C, et al.
Lung Cancer . 2009 Dec; 69(2):155-64. PMID: 19962780
Emodin, a tyrosine kinase inhibitor, is a natural anthraquinone derivative found in the roots and rhizomes of numerous plants; it exhibits an anticancer effect on many malignancies. The most important...
7.
Ko J, Su Y, Lin S, Jhan J, Ciou S, Cheng C, et al.
Biochem Pharmacol . 2009 Oct; 79(4):655-64. PMID: 19799875
Emodin, a tyrosine kinase inhibitor, is a natural anthraquinone derivative found in the roots and rhizomes of numerous plants. Emodin exhibits anticancer effects against a variety of cancer cells, including...
8.
Ko J, Ciou S, Jhan J, Cheng C, Su Y, Chuang S, et al.
Mol Cancer Res . 2009 Aug; 7(8):1378-89. PMID: 19671683
Erlotinib (Tarceva) is a selective epidermal growth factor receptor tyrosine kinase inhibitor in the treatment of human non-small cell lung cancer (NSCLC). In this study, we investigated the roles of...
9.
Chen R, Jhan J, Su Y, Lee W, Cheng C, Ciou S, et al.
Exp Cell Res . 2009 Jun; 315(15):2658-72. PMID: 19505457
Emodin, a tyrosine kinase inhibitor, is a natural anthraquinone derivative found in the roots and rhizomes of numerous plants. It reportedly exhibits an anticancer effect on lung cancer. Gefitinib (Iressa)...