Yin-Kwan Wong
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Explore the profile of Yin-Kwan Wong including associated specialties, affiliations and a list of published articles.
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14
Citations
295
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Recent Articles
1.
Zhu Y, Meng Y, Zhang J, Liu R, Shen S, Gu L, et al.
Int J Biol Sci
. 2024 Nov;
20(14):5510-5530.
PMID: 39494324
Celastrol, a compound derived from traditional Chinese medicine, has therapeutic effects and has been used to treat inflammation-related diseases, cancer, cardiovascular diseases, and neurodegenerative diseases. However, current reviews lack a...
2.
Chen B, Zhang Q, Zhong X, Zhang X, Liu X, Wang H, et al.
Cell Commun Signal
. 2024 Jan;
22(1):75.
PMID: 38287374
Background: Parkinson's disease (PD), a chronic and severe neurodegenerative disease, is pathologically characterized by the selective loss of nigrostriatal dopaminergic neurons. Dopamine (DA), the neurotransmitter produced by dopaminergic neurons, and...
3.
Luo P, An Y, He J, Xing X, Zhang Q, Liu X, et al.
Cancer Lett
. 2024 Jan;
587:216621.
PMID: 38242198
Hepatocellular carcinoma (HCC) is among the deadliest malignancies worldwide and still a pressing clinical problem. Icaritin, a natural compound obtained from the Epimedium genus plant, has garnered significant attention as...
4.
Luo P, Zhang Q, Shen S, An Y, Yuan L, Wong Y, et al.
Asian J Pharm Sci
. 2023 Dec;
18(6):100874.
PMID: 38149060
Hepatocellular carcinoma (HCC) is one of most common and deadliest malignancies. Celastrol (Cel), a natural product derived from the plant, has been extensively researched for its potential effectiveness in fighting...
5.
An Y, Zhang Q, Chen Y, Xia F, Wong Y, He H, et al.
Adv Biol (Weinh)
. 2023 Dec;
8(2):e2300538.
PMID: 38105424
Chronic myelogenous leukemia (CML) that is resistant to tyrosine kinase inhibitors is one of the deadliest hematologic malignancies, and the T315I mutation in the breakpoint cluster region-Abelson (BCR-ABL) kinase domain...
6.
Meng Y, Chen J, Liu Y, Zhu Y, Wong Y, Lyu H, et al.
J Pharm Anal
. 2023 Jan;
12(6):879-888.
PMID: 36605576
The composition of serum is extremely complex, which complicates the discovery of new pharmacodynamic biomarkers via serum proteome for disease prediction and diagnosis. Recently, nanoparticles have been reported to efficiently...
7.
Luo P, Liu D, Zhang Q, Yang F, Wong Y, Xia F, et al.
Acta Pharm Sin B
. 2022 Jun;
12(5):2300-2314.
PMID: 35646542
Ferroptosis is a form of regulated cell death, characterized by excessive membrane lipid peroxidation in an iron- and ROS-dependent manner. Celastrol, a natural bioactive triterpenoid extracted from , shows effective...
8.
Wong Y, Wang J, Lim T, Lin Q, Yap C, Shen H
Proteomics
. 2022 Jan;
22(9):e2100175.
PMID: 35083852
Protein O-GlcNAcylation is a specific form of protein glycosylation that targets a wide range of proteins with important functions. O-GlcNAcylation is known to be deregulated in cancer and has been...
9.
Lyu H, Ma N, Meng Y, Zhang X, Wong Y, Xu C, et al.
Nat Prod Rep
. 2021 Jul;
38(7):1243-1250.
PMID: 34287440
Covering: Up to 2020 Artemisinin has made a significant contribution towards global malaria control since its initial discovery. Countless lives have been saved by this unique and miraculous molecule. In...
10.
Yang J, He Y, Li Y, Zhang X, Wong Y, Shen S, et al.
Pharmacol Ther
. 2020 Oct;
216:107697.
PMID: 33035577
Malaria has been a global epidemic health threat since ancient times. It still claims roughly half a million lives every year in this century. Artemisinin and its derivatives, are frontline...