Yian Ruan
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Explore the profile of Yian Ruan including associated specialties, affiliations and a list of published articles.
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8
Citations
52
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Recent Articles
1.
Ruan Y, Chen S, Brown J, Hadad C, Badjic J
Org Lett
. 2015 Feb;
17(4):852-5.
PMID: 25654486
An amphiphilic basket of type 1 (339 Å(3)) has been found to assemble into unilamellar vesicles in water. The assembled host encapsulates organophosphonates (OPs) (119-185 A(3)) with a particularly high...
2.
Chen S, Ruan Y, Brown J, Hadad C, Badjic J
J Am Chem Soc
. 2014 Nov;
136(49):17337-42.
PMID: 25402739
We used isothermal titration calorimetry to investigate the affinity of basket 1 (470 Å(3)) for trapping variously sized and shaped organophosphonates (OPs) 2-12 (137-244 Å(3)) in water at 298.0 K....
3.
Hermann K, Ruan Y, Hardin A, Hadad C, Badjic J
Chem Soc Rev
. 2014 Jun;
44(2):500-14.
PMID: 24927358
In this review, we describe the construction of gated molecular baskets, discuss their mechanism of action in regulating the exchange of guests and illustrate the potential of these concave hosts...
4.
Ruan Y, Dalkilic E, Peterson P, Pandit A, Dastan A, Brown J, et al.
Chemistry
. 2014 Mar;
20(15):4251-6.
PMID: 24616086
We prepared eleven amino-acid functionalized baskets and used (1) H NMR spectroscopy to quantify their affinity for entrapping dimethyl methylphosphonate (DMMP, 118 Å(3) ) in aqueous phosphate buffer at pH=7.0±0.1;...
5.
Ruan Y, Wang B, Erb J, Chen S, Hadad C, Badjic J
Org Biomol Chem
. 2013 Sep;
11(44):7667-75.
PMID: 24064703
We designed and prepared a spacious and gated basket of type 2 (V = 318 Å(3)) in ten synthetic steps. With the assistance of (1)H NMR spectroscopy, we found that...
6.
Chen S, Ruan Y, Brown J, Gallucci J, Maslak V, Hadad C, et al.
J Am Chem Soc
. 2013 Sep;
135(40):14964-7.
PMID: 24063351
We designed basket 1 to comprise a C3-symmetric hydrophobic cage (477 Å(3)) at its southern edge and three polar ammonium caps at the northern edge. This amphiphilic molecule was observed...
7.
Ruan Y, Taha H, Yoder R, Maslak V, Hadad C, Badjic J
J Phys Chem B
. 2013 Mar;
117(11):3240-9.
PMID: 23445375
We designed, prepared, and characterized three cup-shaped cavitands 1-3 for trapping organophosphonates (O═PR(OR')2, 118-197 Å(3)) whose shape and size correspond to G-type chemical warfare agents (132-186 Å(3)). With the assistance...
8.
Hermann K, Sardini S, Ruan Y, Yoder R, Chakraborty M, Vyas S, et al.
J Org Chem
. 2013 Mar;
78(7):2984-91.
PMID: 23445206
We have developed a novel synthetic method that enables the preparation of functional derivatives of heptiptycene, i.e., cavitands with two juxtaposed cavities. The homocoupling of bicyclic dibromoalkenes is promoted by...