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Yi-Ping Hsueh

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Articles 95
Citations 2018
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Recent Articles
1.
Tian X, Lin T, Lin P, Tsai M, Chen H, Chen W, et al.
Nat Commun . 2024 Dec; 15(1):10911. PMID: 39738207
Taking advantage of the good mechanical strength of expanded Drosophila brains and to tackle their relatively large size that can complicate imaging, we apply potassium (poly)acrylate-based hydrogels for expansion microscopy...
2.
Hsueh Y
Curr Opin Neurobiol . 2024 Dec; 90:102962. PMID: 39731919
Autism spectrum disorders (ASD) are substantially heterogeneous neuropsychiatric conditions with over a thousand associated genetic factors and various environmental influences, such as infection and nutrition. Additionally, males are four times...
3.
Hu H, Wang U, Chen B, Hsueh Y, Wang T
J Lipid Res . 2024 Dec; 66(1):100731. PMID: 39706365
Nuclear lipids play roles in regulatory processes, such as signaling, transcriptional regulation, and DNA repair. In this report, we demonstrate that nuclear lipids may contribute to Ki-67-regulated chromosome integrity during...
4.
Jovanska L, Lin I, Yao J, Chen C, Liu H, Li W, et al.
Nucleic Acids Res . 2024 Jul; 52(16):9551-9573. PMID: 39021337
Trichoderma reesei is an economically important enzyme producer with several unique meiotic features. spo11, the initiator of meiotic double-strand breaks (DSBs) in most sexual eukaryotes, is dispensable for T. reesei...
5.
Hsu T, Huang T, Wang C, Hsueh Y
PLoS Biol . 2024 Jul; 22(7):e3002646. PMID: 39012916
Autism spectrum disorders (ASDs) are considered neural dysconnectivity syndromes. To better understand ASD and uncover potential treatments, it is imperative to know and dissect the connectivity deficits under conditions of...
6.
Hu H, Hsueh Y
J Neurochem . 2024 Jun; 168(9):2155-2169. PMID: 38898681
Kelch-like family member 17 (KLHL17), an actin-associated adaptor protein, is linked to neurological disorders, including infantile spasms and autism spectrum disorders. The key morphological feature of Klhl17-deficient neurons is impaired...
7.
Chuang C, Liu H, Woo T, Chao J, Chen C, Hu H, et al.
Elife . 2024 Feb; 12. PMID: 38393970
Serine(S)/threonine(T)-glutamine(Q) cluster domains (SCDs), polyglutamine (polyQ) tracts and polyglutamine/asparagine (polyQ/N) tracts are Q-rich motifs found in many proteins. SCDs often are intrinsically disordered regions that mediate protein phosphorylation and protein-protein...
8.
Huang T, Shih Y, Yen T, Hsueh Y
Hum Mol Genet . 2024 Feb; 33(11):935-944. PMID: 38382647
Many genes with distinct molecular functions have been linked to genetically heterogeneous amyotrophic lateral sclerosis (ALS), including SuperOxide Dismutase 1 (SOD1) and Valosin-Containing Protein (VCP). SOD1 converts superoxide to oxygen...
9.
Chao Y, Lee Y, Tseng C, Wang L, Hsia K, Chen H, et al.
ACS Nano . 2024 Jan; 18(6):4822-4839. PMID: 38285698
Efficiently delivering exogenous materials into primary neurons and neural stem cells (NSCs) has long been a challenge in neurobiology. Existing methods have struggled with complex protocols, unreliable reproducibility, high immunogenicity,...
10.
Hu H, Lin Y, Wang U, Lee S, Liou Y, Chen B, et al.
PLoS Biol . 2023 Aug; 21(8):e3002274. PMID: 37651441
Dendritic spines, the tiny and actin-rich protrusions emerging from dendrites, are the subcellular locations of excitatory synapses in the mammalian brain that control synaptic activity and plasticity. Dendritic spines contain...