Yexun Wang
Overview
Explore the profile of Yexun Wang including associated specialties, affiliations and a list of published articles.
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7
Citations
302
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Recent Articles
1.
Gong B, Li D, Kusko R, Novoradovskaya N, Zhang Y, Wang S, et al.
Genome Biol
. 2021 Apr;
22(1):109.
PMID: 33863344
Background: Targeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized by the U.S. Food and Drug Administration-led SEquence...
2.
Peng Q, Xu C, Kim D, Lewis M, Dicarlo J, Wang Y
Sci Rep
. 2019 Mar;
9(1):4810.
PMID: 30886209
For specific detection of somatic variants at very low levels, artifacts from the NGS workflow have to be eliminated. Various approaches using unique molecular identifiers (UMI) to analytically remove NGS...
3.
Xu C, Gu X, Padmanabhan R, Wu Z, Peng Q, Dicarlo J, et al.
Bioinformatics
. 2018 Sep;
35(8):1299-1309.
PMID: 30192920
Motivation: Low-frequency DNA mutations are often confounded with technical artifacts from sample preparation and sequencing. With unique molecular identifiers (UMIs), most of the sequencing errors can be corrected. However, errors...
4.
Xu C, Ranjbar M, Wu Z, Dicarlo J, Wang Y
BMC Genomics
. 2017 Jan;
18(1):5.
PMID: 28049435
Background: Detection of DNA mutations at very low allele fractions with high accuracy will significantly improve the effectiveness of precision medicine for cancer patients. To achieve this goal through next...
5.
Peng Q, Vijaya Satya R, Lewis M, Randad P, Wang Y
BMC Genomics
. 2015 Aug;
16:589.
PMID: 26248467
Background: PCR amplicon sequencing has been widely used as a targeted approach for both DNA and RNA sequence analysis. High multiplex PCR has further enabled the enrichment of hundreds of...
6.
Xu H, Dicarlo J, Vijaya Satya R, Peng Q, Wang Y
BMC Genomics
. 2014 Apr;
15:244.
PMID: 24678773
Background: High-throughput sequencing is rapidly becoming common practice in clinical diagnosis and cancer research. Many algorithms have been developed for somatic single nucleotide variant (SNV) detection in matched tumor-normal DNA...
7.
Li Z, Branham W, Dial S, Wang Y, Guo L, Shi L, et al.
BMC Genomics
. 2010 Oct;
11:609.
PMID: 21029445
Background: Dysregulated expression of microRNAs (miRNAs) has been previously observed in human cancer tissues and shown promise in defining tumor status. However, there is little information as to if or...