Yevgenia Tesmenitsky
Overview
Explore the profile of Yevgenia Tesmenitsky including associated specialties, affiliations and a list of published articles.
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17
Citations
961
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Recent Articles
1.
Molinaro R, Yu M, Sausen G, Bichsel C, Corbo C, Folco E, et al.
Cardiovasc Res
. 2021 Mar;
117(13):2652-2663.
PMID: 33751034
Aims: Recent evidence suggests that 'vulnerable plaques', which have received intense attention as underlying mechanism of acute coronary syndromes over the decades, actually rarely rupture and cause clinical events. Superficial...
2.
Wara A, Wang S, Wu C, Fang F, Haemmig S, Weber B, et al.
Cell Rep
. 2020 Dec;
33(13):108550.
PMID: 33378664
CD4 T cells regulate inflammation and metabolism in obesity. An imbalance of CD4 T regulatory cells (Tregs) is critical in the development of insulin resistance and diabetes. Although cytokine control...
3.
A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
Simion V, Zhou H, Haemmig S, Pierce J, Mendes S, Tesmenitsky Y, et al.
Nat Commun
. 2020 Dec;
11(1):6135.
PMID: 33262333
Long non-coding RNAs (lncRNAs) are emerging regulators of pathophysiological processes including atherosclerosis. Using RNA-seq profiling of the intima of lesions, here we identify a macrophage-specific lncRNA MAARS (Macrophage-Associated Atherosclerosis lncRNA...
4.
Simion V, Zhou H, Pierce J, Yang D, Haemmig S, Tesmenitsky Y, et al.
JCI Insight
. 2020 Oct;
5(21).
PMID: 33021969
Long noncoding RNAs (lncRNAs) play important roles in regulating diverse cellular processes in the vessel wall, including atherosclerosis. RNA-Seq profiling of intimal lesions revealed a lncRNA, VINAS (Vascular INflammation and...
5.
Haemmig S, Yang D, Sun X, Das D, Ghaffari S, Molinaro R, et al.
Sci Transl Med
. 2020 Feb;
12(531).
PMID: 32075942
Long noncoding RNAs (lncRNAs) are emerging regulators of biological processes in the vessel wall; however, their role in atherosclerosis remains poorly defined. We used RNA sequencing to profile lncRNAs derived...
6.
Vromman A, Ruvkun V, Shvartz E, Wojtkiewicz G, Masson G, Tesmenitsky Y, et al.
Eur Heart J
. 2019 Jan;
40(30):2482-2491.
PMID: 30698710
Aims: Targeting interleukin-1 (IL-1) represents a novel therapeutic approach to atherosclerosis. CANTOS demonstrated the benefits of IL-1β neutralization in patients post-myocardial infarction with residual inflammatory risk. Yet, some mouse data...
7.
Franck G, Mawson T, Folco E, Molinaro R, Ruvkun V, Engelbertsen D, et al.
Circ Res
. 2018 Mar;
123(1):33-42.
PMID: 29572206
Rationale: Neutrophils likely contribute to the thrombotic complications of human atheromata. In particular, neutrophil extracellular traps (NETs) could exacerbate local inflammation and amplify and propagate arterial intimal injury and thrombosis....
8.
Franck G, Mawson T, Sausen G, Salinas M, Masson G, Cole A, et al.
Circ Res
. 2017 Apr;
121(1):31-42.
PMID: 28428204
Rationale: Superficial erosion currently causes up to a third of acute coronary syndromes; yet, we lack understanding of its mechanisms. Thrombi because of superficial intimal erosion characteristically complicate matrix-rich atheromata...
9.
Quillard T, Araujo H, Franck G, Tesmenitsky Y, Libby P
Arterioscler Thromb Vasc Biol
. 2014 Apr;
34(6):1179-86.
PMID: 24723558
Objective: Substantial evidence implicates interstitial collagenases of the matrix metalloproteinase (MMP) family in plaque rupture and fatal thrombosis. Understanding the compensatory mechanisms that may influence the expression of these enzymes...
10.
Sawada N, Jiang A, Takizawa F, Safdar A, Manika A, Tesmenitsky Y, et al.
Cell Metab
. 2014 Feb;
19(2):246-58.
PMID: 24506866
Endothelial dysfunction is a central hallmark of diabetes. The transcriptional coactivator PGC-1α is a powerful regulator of metabolism, but its role in endothelial cells remains poorly understood. We show here...