Yee-Shiuan Chen
Overview
Explore the profile of Yee-Shiuan Chen including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
1023
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0
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Recent Articles
1.
Chen Y, Chen I, Pham G, Shao T, Bangar H, Way S, et al.
J Clin Invest
. 2020 Jan;
130(5):2377-2390.
PMID: 31990686
Colitis caused by Clostridium difficile infection is a growing cause of human morbidity and mortality, especially after antibiotic use in health care settings. The natural immunity of newborn infants and...
2.
Chen Y, Memon P
BMJ Case Rep
. 2019 Jul;
12(7).
PMID: 31300601
This is a rare case of sporadic lymphangioleiomyomatosis (S-LAM) manifesting as refractory chylothorax and chyloperitoneum. A middle-aged woman with unremarkable medical history presented with respiratory failure, abdominal distension and anasarca....
3.
Bobo L, El Feghaly R, Chen Y, Dubberke E, Han Z, Baker A, et al.
Infect Immun
. 2012 Dec;
81(3):713-22.
PMID: 23264053
Clostridium difficile infection (CDI) results in toxin-induced epithelial injury and marked intestinal inflammation. Fecal markers of intestinal inflammation correlate with CDI disease severity, but regulation of the inflammatory response is...
4.
Matsushita H, Vesely M, Koboldt D, Rickert C, Uppaluri R, Magrini V, et al.
Nature
. 2012 Feb;
482(7385):400-4.
PMID: 22318521
Cancer immunoediting, the process by which the immune system controls tumour outgrowth and shapes tumour immunogenicity, is comprised of three phases: elimination, equilibrium and escape. Although many immune components that...
5.
Bodyak N, Ayus J, Achinger S, Shivalingappa V, Ke Q, Chen Y, et al.
Proc Natl Acad Sci U S A
. 2007 Oct;
104(43):16810-5.
PMID: 17942703
Observations in hemodialysis patients suggest a survival advantage associated with activated vitamin D therapy. Left ventricular (LV) structural and functional abnormalities are strongly linked with hemodialysis mortality. Here, we investigated...
6.
Bodyak N, Rigor D, Chen Y, Han Y, Bisping E, Pu W, et al.
Am J Physiol Heart Circ Physiol
. 2007 May;
293(1):H829-35.
PMID: 17468330
Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane proton carrier that uncouples ATP synthesis. The aim of this study was to determine whether UCP2 plays a role in survival...
7.
Han Y, Chen Y, Liu Z, Bodyak N, Rigor D, Bisping E, et al.
Circ Res
. 2006 Jul;
99(4):415-23.
PMID: 16857965
Caspase-9 is a critical regulator of mitochondria-mediated apoptosis. We found that adult cardiac myocytes, but not nonmyocytes, have high caspase-9 expression, and exhibit relative resistance to caspase-9-induced cell death. Thus,...
8.
Chen C, Cheng T, Lin H, Shih N, Chen Y, Chen Y, et al.
Mol Pharmacol
. 2006 Jan;
69(4):1347-55.
PMID: 16391241
Endothelin-1 (ET-1) is implicated in fibroblast proliferation, which results in cardiac fibrosis. Both reactive oxygen species (ROS) generation and epidermal growth factor receptor (EGFR) transactivation play critical roles in ET-1...
9.
Cheng T, Shih N, Chen C, Lin H, Liu J, Chao H, et al.
J Biomed Sci
. 2005 May;
12(1):123-33.
PMID: 15864745
Endothelin-1 (ET-1) has been found to increase cardiac beta-myosin heavy chain (beta-MyHC) gene expression and induce hypertrophy in cardiomyocytes. ET-1 has been demonstrated to increase intracellular reactive oxygen species (ROS)...