Yea Seul Shin
Overview
Explore the profile of Yea Seul Shin including associated specialties, affiliations and a list of published articles.
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5
Citations
198
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Recent Articles
1.
Shin Y, Ryall J, Britto J, Lau C, Devenish R, Nagley P, et al.
J Neurochem
. 2019 Jan;
149(2):269-283.
PMID: 30664245
Contributions of damaged mitochondria to neuropathologies have stimulated interest in mitophagy. We investigated triggers of neuronal mitophagy by disruption of mitochondrial energy metabolism in primary neurons. Mitophagy was examined in...
2.
Bonello F, Hassoun S, Mouton-Liger F, Shin Y, Muscat A, Tesson C, et al.
Hum Mol Genet
. 2019 Jan;
28(10):1645-1660.
PMID: 30629163
Mutations of LRRK2, encoding leucine-rich repeat kinase 2 (LRRK2), are the leading cause of autosomal dominant Parkinson's disease (PD). The most frequent of these mutations, G2019S substitution, increases kinase activity,...
3.
Perera N, Sheean R, Lau C, Shin Y, Beart P, Horne M, et al.
Autophagy
. 2017 Oct;
14(3):534-551.
PMID: 28980850
Macroautophagy/autophagy is the main intracellular catabolic pathway in neurons that eliminates misfolded proteins, aggregates and damaged organelles associated with ageing and neurodegeneration. Autophagy is regulated by both MTOR-dependent and -independent...
4.
Higgins G, Beart P, Shin Y, Chen M, Cheung N, Nagley P
J Alzheimers Dis
. 2010 May;
20 Suppl 2:S453-73.
PMID: 20463398
Oxidative stress plays a central role in neuronal injury and cell death in acute and chronic pathological conditions. The cellular responses to oxidative stress embrace changes in mitochondria and other...
5.
Diwakarla S, Mercer L, Kardashsyan L, Chu P, Shin Y, Lau C, et al.
J Neurochem
. 2009 Apr;
109 Suppl 1:198-206.
PMID: 19393028
GABAergic striatal neurons are compromised in basal ganglia pathologies and we analysed how insult nature determined their patterns of injury and recruitment of the intrinsic mitochondrial pathway during programmed cell...