Ye Leng
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Explore the profile of Ye Leng including associated specialties, affiliations and a list of published articles.
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21
Citations
456
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Recent Articles
1.
Huang H, Cui D, Leng Y, Zhang K, Yu A, Wang Y, et al.
Front Med (Lausanne)
. 2023 Feb;
10:1063648.
PMID: 36814778
Background: Conducting geriatric trials is the most feasible way to address the vast underrepresentation of older adults in clinical trials of cancer therapies. This study is a globally comprehensive examination...
2.
Huang H, Tang Y, Yu Y, Yu A, Wu D, Fang H, et al.
Lancet Reg Health West Pac
. 2022 Nov;
31:100624.
PMID: 36426285
Overall survival (OS) is considered the standard clinical endpoint to support effectiveness claims in new drug applications globally, particularly for lethal conditions such as cancer. However, the source and reliability...
3.
Huang H, Liu M, Li X, Meng X, Cui D, Leng Y, et al.
Zhongguo Fei Ai Za Zhi
. 2022 Oct;
25(10):730-734.
PMID: 36285392
Bayesian statistics is an approach for learning from evidences as it accumulates, combining prior distribution with current information on a quantity of interest, in which posterior distribution and inferences are...
4.
Li B, He S, Liu R, Huang L, Liu G, Wang R, et al.
J Ethnopharmacol
. 2019 Jul;
243:112121.
PMID: 31356966
Ethnopharmacological Relevance: Psoriasis is an immune system meditated disease, especially T cells. It disturbed many people around the world and hard to therapy. Paeonia lactiflora Pall has been used as...
5.
Li A, Chen P, Leng Y, Kang J
Oncogene
. 2018 Jul;
37(45):5952-5966.
PMID: 29980788
Cancer-associated fibroblasts (CAFs) are important components in breast tumors and essential for tumor progression and metastasis. However, the role of epigenetic modification in driving the function of CAFs within breast...
6.
Yang D, Qiao J, Wang G, Lan Y, Li G, Guo X, et al.
Nucleic Acids Res
. 2018 Mar;
46(8):3906-3920.
PMID: 29529255
Previous studies have revealed the critical roles of N6-methyladenosine (m6A) modification of mRNA in embryonic stem cells (ESCs), but the biological function of m6A in large intergenic noncoding RNA (lincRNA)...
7.
Duan H, Ding L, Li X, Hu L, Wen A, Leng Y, et al.
J Pharm Anal
. 2018 Feb;
3(2):84-92.
PMID: 29403801
Simple, rapid and specific liquid chromatography-mass spectrometry (LC-MS) methods have been developed and validated for the quantification of cefcapene acid in human plasma and urine. Plasma samples were simply pretreated...
8.
Jing R, Xi J, Leng Y, Chen W, Wang G, Jia W, et al.
Oncotarget
. 2017 May;
8(25):40654-40667.
PMID: 28489565
Centromere protein A (CENP-A) is a variant of core histone H3 that marks the centromere's location on the chromosome. The mechanisms that target the protein to the nucleus and the...
9.
Yang Y, Huang Y, Wang Z, Wang H, Duan B, Ye D, et al.
Oncotarget
. 2016 Jul;
7(37):59388-59401.
PMID: 27449083
Histone deacetylase 10 (HDAC10) is a member of the class II HDACs, and its role in cancer is emerging. In this study, we found that HDAC10 is highly expressed in...
10.
Zhu S, Jing R, Yang Y, Huang Y, Wang X, Leng Y, et al.
J Biol Chem
. 2015 Mar;
290(18):11282-92.
PMID: 25814666
Human BUB3 is a key mitotic checkpoint factor that recognizes centromeric components and recruits other mitotic checkpoint molecules to the unattached kinetochore. The key amino acid residues responsible for its...