Yayoi Hayashi
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Explore the profile of Yayoi Hayashi including associated specialties, affiliations and a list of published articles.
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25
Citations
214
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Recent Articles
11.
Kato R, Yuasa H, Inoue K, Iwao T, Tanaka K, Ooi K, et al.
Drug Metab Pharmacokinet
. 2007 May;
22(2):96-102.
PMID: 17495416
Lactobacillus casei Shirota strain (L. casei) has a modulating effect on the production of cytokines, which often play important roles in drug metabolism, in the inflamed intestinal mucosa. We evaluated...
12.
Nakai Y, Inoue K, Abe N, Hatakeyama M, Ohta K, Otagiri M, et al.
J Pharmacol Exp Ther
. 2007 May;
322(2):469-76.
PMID: 17475902
The functional characteristics of human proton coupled folate transporter (hPCFT)/heme carrier protein (HCP) 1 were investigated. hPCFT/HCP1 expressed transiently in human embryonic kidney 293 cells mediated the transport of folate...
13.
Ohta K, Inoue K, Hayashi Y, Yuasa H
Drug Metab Dispos
. 2006 Aug;
34(11):1868-74.
PMID: 16928787
We have cloned and functionally characterized the rat ortholog of multidrug and toxin extrusion type transporter 1 (rMATE1). The mRNA of rMATE1 was strongly expressed in kidney and detectable in...
14.
Ohta K, Inoue K, Hayashi Y, Yuasa H
Biol Pharm Bull
. 2006 Apr;
29(4):785-9.
PMID: 16595918
Studies using the closed loop and everted sacs of the rat small intestine recently prompted us to suggest that carrier-mediated transport is involved in the intestinal absorption of glycerol. Although...
15.
Glycerol uptake in HCT-15 human colon cancer cell line by Na(+)-dependent carrier-mediated transport
Fujimoto N, Inoue K, Hayashi Y, Yuasa H
Biol Pharm Bull
. 2006 Jan;
29(1):150-4.
PMID: 16394529
It has recently been suggested that an Na(+)-dependent carrier-mediated transport system is involved in intestinal glycerol absorption. Such a transport system is of general interest as a possible pathway of...
16.
Kato T, Hayashi Y, Inoue K, Yuasa H
Biol Pharm Bull
. 2005 Mar;
28(3):553-5.
PMID: 15744090
The absorption of glycerol was examined using the closed loop of the rat small intestine in situ to clarify the transport mechanism. The absorption of glycerol, evaluated by its disappearance...
17.
Iwao T, Inoue K, Hayashi Y, Yuasa H, Watanabe J
Drug Metab Pharmacokinet
. 2005 Feb;
19(6):430-7.
PMID: 15681897
The metabolic extraction of diltiazem was examined in conjunction with its absorption, using rat small intestine perfused in situ by the single-pass method, to clarify its intestinal metabolism. This is...
18.
Iwao T, Inoue K, Hayashi Y, Yuasa H, Watanabe J
Drug Metab Pharmacokinet
. 2004 Dec;
17(6):546-53.
PMID: 15618710
Nifedipine is one of drugs that have been suggested to undergo significant first-pass metabolism by cytochrome P450 (CYP) 3A in the intestine, based mainly on pharmacokinetic analyses of in vivo...
19.
Kato T, Hayashi Y, Inoue K, Yuasa H
Biol Pharm Bull
. 2004 Nov;
27(11):1826-30.
PMID: 15516731
The mechanism of intestinal glycerol transport was investigated by using the in vitro everted sac method involving the rat small intestine. The uptake of glycerol into everted sacs was saturable...
20.
Tokui K, Kimata T, Uchida K, Yuasa H, Hayashi Y, Itatsu T, et al.
Ther Drug Monit
. 2004 May;
26(3):287-94.
PMID: 15167630
The present study aims to determine the population pharmacokinetic parameters of cyclosporine (CsA) after multiple oral administration of the microemulsion formulation, Neoral, in kidney transplant patients and to propose a...