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Yaxian Huang

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Huang J, Huang Y, Feng X, Huang C, Huang M, Wen Z, et al.
Neurosurg Rev . 2024 Oct; 47(1):809. PMID: 39436476
Flow-diverter devices (FDs) are effective in treating intracranial aneurysms (IAs) but carry substantial periprocedural risks, particularly ischemic complications. This study aimed to determine if elevated Systemic Immune-Inflammation Index (SII) can...
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Wei B, Liu W, Jin L, Huang Y, Cheng W, Fan H, et al.
Cell Death Dis . 2024 Aug; 15(8):569. PMID: 39107268
Subarachnoid hemorrhage (SAH) significantly compromises the blood-brain barrier (BBB) and impairs patient recovery. This study elucidates the critical role of astrocytic Neogenin-1 (NEO1) in BBB integrity post-SAH and examines the...
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Liu Z, Cai J, Jiang G, Wang M, Wu C, Su K, et al.
Eur J Med Chem . 2023 Nov; 263:115968. PMID: 37995563
Platinum-based chemotherapeutics are widely used for cancer treatment but are frequently limited because of dosage-dependent side effects and drug resistance. To attenuate these drawbacks, a series of novel platinum(IV) prodrugs...
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Wu J, Huang Y, Zhan C, Chen L, Lin Z, Song Z
iScience . 2023 Sep; 26(9):107618. PMID: 37664614
Treatment of periodontitis in people with diabetes remains challenging. The present study aimed to investigate the therapeutic potential of thioredoxin-1 (TRX1) in periodontitis with diabetes, as well as its role...
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Zhan C, Zhou Z, Huang Y, Huang S, Lin Z, He F, et al.
Gastroenterol Rep (Oxf) . 2023 Jul; 11:goad041. PMID: 37456714
Background: Periodontitis disease (PD) is associated with a systemic disorder of inflammatory bowel disease (IBD). The immune response is the common feature of the two conditions, but the more precise...
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Huang Y, Wu J, Zhan C, Liu R, Zhou Z, Huang X, et al.
Front Pharmacol . 2023 Jun; 14:1119847. PMID: 37261283
The enhanced osteoclastogenesis contributes to alveolar bone resorption in periodontitis, which increases the risk of tooth loss. To reduce bone destruction, the inhibition of osteoclast development is proposed as a...