Yau Mun Lim
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Explore the profile of Yau Mun Lim including associated specialties, affiliations and a list of published articles.
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8
Citations
115
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Recent Articles
1.
Rouatbi N, Walters A, Zam A, Lim Y, Marrocu A, Liam-Or R, et al.
Adv Sci (Weinh)
. 2025 Jan;
:e2407262.
PMID: 39888280
Immune checkpoint (ICP) blockade has shown limited effectiveness in glioblastoma (GBM), particularly in the mesenchymal subtype, where interactions between immune cells and glioblastoma cancer stem cells (GSCs) drive immunosuppression and...
2.
Liu J, Binding L, Puntambekar I, Patodia S, Lim Y, Mryzyglod A, et al.
Acta Neuropathol
. 2024 Oct;
148(1):49.
PMID: 39377933
White matter microvascular alterations in temporal lobe epilepsy (TLE) may be relevant to acquired neurodegenerative processes and cognitive impairments associated with this condition. We quantified microvascular changes, myelin, axonal, glial...
3.
Constantinou M, Nicholson J, Zhang X, Maniati E, Lucchini S, Rosser G, et al.
Cell Rep
. 2024 Jun;
43(6):114309.
PMID: 38848215
Glioblastomas are the most common malignant brain tumors in adults; they are highly aggressive and heterogeneous and show a high degree of plasticity. Here, we show that methyltransferase-like 7B (METTL7B)...
4.
Lam H, Patodia S, Zeicu C, Lim Y, Mrzyglod A, Scott C, et al.
Epilepsia
. 2024 Jun;
65(8):2368-2385.
PMID: 38837385
Objective: Amygdala enlargement can occur in temporal lobe epilepsy, and increased amygdala volume is also reported in sudden unexpected death in epilepsy (SUDEP). Apnea can be induced by amygdala stimulation,...
5.
Boot J, Rosser G, Kancheva D, Vinel C, Lim Y, Pomella N, et al.
Elife
. 2022 Nov;
11.
PMID: 36412091
We describe a subset of glioblastoma, the most prevalent malignant adult brain tumour, harbouring a bias towards hypomethylation at defined differentially methylated regions. This epigenetic signature correlates with an enrichment...
6.
Patodia S, Lim Y, Chung F, Stylianou I, El Hachami H, Thom M
Epilepsia
. 2022 Jun;
63(9):2427-2438.
PMID: 35716147
Objectives: Dysfunctional connectivity and preexisting structural abnormalities of central autonomic network (CAN) regions have been shown on magnetic resonance imaging (MRI) in sudden unexpected death in epilepsy (SUDEP) and may...
7.
Badodi S, Pomella N, Lim Y, Brandner S, Morrison G, Pollard S, et al.
Neuro Oncol
. 2022 Feb;
24(8):1273-1285.
PMID: 35213723
Background: Epigenetic changes play a key role in the pathogenesis of medulloblastoma (MB), the most common malignant pediatric brain tumor. Methods: We explore the therapeutic potential of BMI1 and MAPK/ERK...
8.
Badodi S, Pomella N, Zhang X, Rosser G, Whittingham J, Niklison-Chirou M, et al.
Nat Commun
. 2021 Apr;
12(1):2148.
PMID: 33846320
Deregulation of chromatin modifiers plays an essential role in the pathogenesis of medulloblastoma, the most common paediatric malignant brain tumour. Here, we identify a BMI1-dependent sensitivity to deregulation of inositol...
9.
Ashton N, Leuzy A, Lim Y, Troakes C, Hortobagyi T, Hoglund K, et al.
Acta Neuropathol Commun
. 2019 Jan;
7(1):5.
PMID: 30626432
Alzheimer's disease (AD) is pathologically characterized by the accumulation of amyloid-β (Aβ) plaques, neurofibrillary tangles and widespread neuronal loss in the brain. In recent years, blood biomarkers have emerged as...