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Yasushi Hiraoka

Explore the profile of Yasushi Hiraoka including associated specialties, affiliations and a list of published articles. Areas
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Articles 189
Citations 5882
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Recent Articles
1.
Asakawa H, Nagao K, Fukagawa T, Obuse C, Hiraoka Y, Haraguchi T
J Biochem . 2024 Dec; PMID: 39727334
Nuclear pore complexes (NPCs) act as gateways across the nuclear envelope for molecular transport between the nucleus and the cytoplasm in eukaryotes. NPCs consist of several subcomplexes formed by multiple...
2.
Ding D, Okamasa K, Yoshimura Y, Matsuda A, Yamamoto T, Hiraoka Y, et al.
FASEB J . 2024 Nov; 38(21):e70163. PMID: 39520300
Pairing of homologous chromosomes during meiosis is crucial for successful sexual reproduction. Previous studies have shown that the fission yeast sme2 RNA, a meiosis-specific long noncoding RNA (lncRNA), accumulates at...
3.
Yonezawa N, Shindo T, Oda H, Kimura H, Hiraoka Y, Haraguchi T, et al.
Genes Cells . 2024 Aug; 29(10):820-837. PMID: 39140385
In eukaryotes, DNA is housed within the cell nucleus. Molecules required for the formation of a nucleus have been identified using in vitro systems with frog egg extracts and in...
4.
Takahata S, Taguchi A, Takenaka A, Mori M, Chikashige Y, Tsutsumi C, et al.
Genes Cells . 2024 Jun; 29(7):567-583. PMID: 38837646
Chromatin condensation state is the key for retrieving genetic information. High-mobility group protein (HMG) proteins exhibit DNA-binding and bending activities, playing an important role in the regulation of chromatin structure....
5.
Hirano Y, Sato T, Miura A, Kubota Y, Shindo T, Fukase K, et al.
J Biol Chem . 2024 Jun; 300(7):107430. PMID: 38825008
The nuclear envelope (NE) is a permeable barrier that maintains nuclear-cytoplasmic compartmentalization and ensures nuclear function; however, it ruptures in various situations such as mechanical stress and mitosis. Although the...
6.
Khanh Le T, Hirano Y, Asakawa H, Okamoto K, Fukagawa T, Haraguchi T, et al.
J Cell Sci . 2024 Feb; 137(2). PMID: 38314868
No abstract available.
7.
Khanh Le T, Hirano Y, Asakawa H, Okamoto K, Fukagawa T, Haraguchi T, et al.
J Cell Sci . 2023 Sep; 136(19). PMID: 37694715
Aberrant accumulation of inner nuclear membrane (INM) proteins is associated with deformed nuclear morphology and mammalian diseases. However, the mechanisms underlying the maintenance of INM homeostasis remain poorly understood. In...
8.
Hirano Y, Ohno Y, Kubota Y, Fukagawa T, Kihara A, Haraguchi T, et al.
J Cell Sci . 2023 Apr; 136(10). PMID: 37078207
Maintaining the integrity of the nuclear envelope (NE) is essential for preventing genomic DNA damage. Recent studies have shown that enzymes that catalyze lipid synthesis are involved in NE maintenance,...
9.
Hirano Y, Kinugasa Y, Kubota Y, Obuse C, Haraguchi T, Hiraoka Y
J Biochem . 2023 Feb; 174(1):33-46. PMID: 36799444
The nuclear envelope (NE) is a double-membrane structure consisting of inner and outer membranes that spatially separate the nucleus from the cytoplasm, and its function is critical for cellular functions...
10.
Yang H, Asakawa H, Li F, Haraguchi T, Shih H, Hiraoka Y
Genes Cells . 2022 Dec; 28(3):188-201. PMID: 36562208
The nuclear pore complex (NPC) provides a permeable barrier between the nucleoplasm and cytoplasm. In a subset of NPC constituents that regulate meiosis in the fission yeast Schizosaccharomyces pombe, we...