Yasuaki Mohri
Overview
Explore the profile of Yasuaki Mohri including associated specialties, affiliations and a list of published articles.
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20
Citations
1412
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Recent Articles
1.
Yang J, Hayano M, Griffin P, Amorim J, Bonkowski M, Apostolides J, et al.
Cell
. 2024 Mar;
187(5):1312-1313.
PMID: 38428398
No abstract available.
2.
Matsumura H, Liu N, Nanba D, Ichinose S, Takada A, Kurata S, et al.
Nat Aging
. 2023 Apr;
1(2):190-204.
PMID: 37118636
Hair follicles, mammalian mini-organs that grow hair, miniaturize during aging, leading to hair thinning and loss. Here we report that hair follicle stem cells (HFSCs) lose their regenerative capabilities during...
3.
Yang J, Hayano M, Griffin P, Amorim J, Bonkowski M, Apostolides J, et al.
Cell
. 2023 Jan;
186(2):305-326.e27.
PMID: 36638792
All living things experience an increase in entropy, manifested as a loss of genetic and epigenetic information. In yeast, epigenetic information is lost over time due to the relocalization of...
4.
Kato T, Liu N, Morinaga H, Asakawa K, Muraguchi T, Muroyama Y, et al.
Dev Cell
. 2021 Dec;
56(24):3309-3320.e5.
PMID: 34932948
Maintaining genomic integrity and stability is crucial for life; yet, no tissue-driven mechanism that robustly safeguards the epithelial genome has been discovered. Epidermal stem cells (EpiSCs) continuously replenish the stratified...
5.
Eshiba S, Namiki T, Mohri Y, Aida T, Serizawa N, Shibata T, et al.
Cell Rep
. 2021 Aug;
36(5):109492.
PMID: 34348144
Early differential diagnosis between malignant and benign tumors and their underlying intrinsic differences are the most critical issues for life-threatening cancers. To study whether human acral melanomas, deadly cancers that...
6.
Morinaga H, Mohri Y, Grachtchouk M, Asakawa K, Matsumura H, Oshima M, et al.
Nature
. 2021 Jun;
595(7866):266-271.
PMID: 34163066
Obesity is a worldwide epidemic that predisposes individuals to many age-associated diseases, but its exact effects on organ dysfunction are largely unknown. Hair follicles-mini-epithelial organs that grow hair-are miniaturized by...
7.
Sun Q, Lee W, Mohri Y, Takeo M, Lim C, Xu X, et al.
Nat Commun
. 2019 Nov;
10(1):5023.
PMID: 31685822
Melanoma, the deadliest skin cancer, remains largely incurable at advanced stages. Currently, there is a lack of animal models that resemble human melanoma initiation and progression. Recent studies using a...
8.
Liu N, Matsumura H, Kato T, Ichinose S, Takada A, Namiki T, et al.
Nature
. 2019 Apr;
568(7752):344-350.
PMID: 30944469
Stem cells underlie tissue homeostasis, but their dynamics during ageing-and the relevance of these dynamics to organ ageing-remain unknown. Here we report that the expression of the hemidesmosome component collagen...
9.
Yamakami Y, Kohashi K, Oyama K, Mohri Y, Hidema S, Nishimori K
Biochem Biophys Rep
. 2017 Sep;
8:174-183.
PMID: 28955954
Tooth development requires proliferation, differentiation, and specific migration of dental epithelial cells, through well-organized signaling interactions with mesenchymal cells. Recently, it has been reported that leucine-rich repeat-containing G protein coupled...
10.
Matsumura H, Mohri Y, Thanh Binh N, Morinaga H, Fukuda M, Ito M, et al.
Science
. 2016 Feb;
351(6273):aad4395.
PMID: 26912707
Hair thinning and loss are prominent aging phenotypes but have an unknown mechanism. We show that hair follicle stem cell (HFSC) aging causes the stepwise miniaturization of hair follicles and...