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Yash Kapoor

Explore the profile of Yash Kapoor including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 159
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Recent Articles
1.
Milewski M, Murashov M, Kapoor Y, Zhang J, Zhu W, Cueto M, et al.
Mol Pharm . 2024 Sep; 21(10):4947-4959. PMID: 39226331
Subcutaneous delivery of monoclonal antibody therapeutics is often preferred to intravenous delivery due to better patient compliance and overall lower cost to the healthcare system. However, the systemic absorption of...
2.
Kapoor Y, Meyer R, Ferguson H, Skomski D, Daublain P, Troup G, et al.
Mol Pharm . 2021 Jun; 18(7):2455-2469. PMID: 34165309
The process of bringing a drug to market involves innumerable decisions to refine a concept into a final product. The final product goes through extensive research and development to meet...
3.
Li Z, Biswas A, Finkelstein J, Grein S, Kapoor Y, Milewski M, et al.
J Pharm Sci . 2020 Nov; 110(3):1279-1291.e1. PMID: 33248056
A dermal absorption model for small and macromolecules was previously proposed by Ibrahim et al. This model estimated absorption of therapeutics from the dermal tissue based on their molecular size...
4.
Kapoor Y, Milewski M, Dick L, Zhang J, Bothe J, Gehrt M, et al.
Biomed Microdevices . 2019 Dec; 22(1):7. PMID: 31845070
Minimally invasive delivery of peptide and protein molecules represents a significant opportunity for product differentiation and value creation versus standard injectable routes of administration. One such technology utilizes microneedle (MN)...
5.
Milewski M, Kapoor Y, Ding Z, Zhang J, Ghartey-Tagoe E, Manser K, et al.
J Pharm Sci . 2019 Nov; 109(3):1288-1296. PMID: 31730776
The formulation of biotherapeutics presents unique challenges especially with regard to physical and chemical stability and often requires refrigerated storage conditions of final drug products. Peptide A is an example...
6.
Smith D, Kapoor Y, Hermans A, Nofsinger R, Kesisoglou F, Gustafson T, et al.
Int J Pharm . 2018 Sep; 550(1-2):418-428. PMID: 30172750
Drug development is a long process which requires careful evaluation of the drug substance (active pharmaceutical ingredient, API), drug product (tablet, capsule etc.) and the bioperformance (both pre-clinical and clinical)...
7.
Smith D, Kapoor Y, Klinzing G, Procopio A
Int J Pharm . 2018 Apr; 544(1):21-30. PMID: 29605694
Fused deposition modeling (FDM) 3D printing (3DP) has a potential to change how we envision manufacturing in the pharmaceutical industry. A more common utilization for FDM 3DP is to build...
8.
Kapoor Y, Dixon P, Sekar P, Chauhan A
Eur J Pharm Biopharm . 2017 Aug; 120:73-79. PMID: 28823714
Cyclosporine A is prescribed for a number of ophthalmic applications such as dry eyes, uveitis in children and adolescents, vernal keratoconjunctivitis, and peripheral ulcerative keratitis. Extended release of cyclosporine from...
9.
Leung D, Kapoor Y, Alleyne C, Walsh E, Leithead A, Habulihaz B, et al.
AAPS PharmSciTech . 2017 Jan; 18(6):2203-2213. PMID: 28070846
Parenteral delivery remains a compelling drug delivery route for both large- and small-molecule drugs and can bypass issues encountered with oral absorption. For injectable drug products, there is a strong...
10.
Kapoor Y, Milewski M, Mitra A, Kasting G
J Pharm Sci . 2016 Feb; 105(3):1341-4. PMID: 26886328
Delivery through the skin, either through topical application for therapeutic or cosmetic benefits or intradermal delivery through emerging technologies such as microneedles, has been studied extensively in past decades. In...